Clinical trial · Interventional
Effects of Oxygen After Abdominal Oncological Surgery
Exploring Postoperative Effects of Hyperoxic Intermittent Stimuli on Reticulocytes Levels in Abdominal Surgery: A Randomized Single-blind Study
NCT06321874CI-TRIAL-00075905EPHIRAScompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aims of the research is to determine whether a Hyperoxic intermittent stimuli protocol can increase reticulocyte counts, signififying a rise in EPO production, in patients undergoing abdominal surgery
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Abdominal Cancer | Malignant Abdominal Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Oxygen | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Normobaric Oxygen Paradox (NOP) group
- description
- The NOP group received 60% oxygen for two hours on days 1, 3, and 5 post-surgery using a venti-mask.
- interventionNames
- Procedure: Oxygen
- type
- NO_INTERVENTION
- label
- Control (CTR) group
- description
- The CTR group did not receive oxygen therapy during the post-operatory period starting from day 1.
Primary outcomes (1)
- measure
- Percentage change in reticulocyte count
- timeFrame
- 6 days
- description
- Percentage change in reticulocyte count from baseline to day six within each group
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * patients undergoing abdominal oncological surgery Exclusion Criteria: * GFR\<60 ml/minute and/ or creatinine serum level \> 2mg/dl * Transfusion of red blood cells per or postoperatively * Bleeding requiring repeated transfusions during or after surgery * Severe respiratory syndrome necessitating continuous oxygen * Intolerance to oxygen mask
References
Publications (0)
Data not yet available
No reference posted for this study.