Clinical trial · Interventional
Effects of Perioperative Immunonutrition in Patients With Head and Neck Cancer
A Randomized Clinical Trial With Perioperative Immunonutrition Support on Anthropometric, Clinical and Biochemical Parameters of Head and Neck Cancer Patients Undergoing Surgery
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A prospective randomized controlled study compared the effects of perioperative immunonutrition and standard enteral nutrition (EN) on postoperative short-term outcomes of patients with head and neck (HNC). Five days before surgery and the postoperative day 10, immunonutrition support was given to the intervention group (n=17), and standard EN support was given to the control group (n=17). Body analyses were made, food consumption records were taken, NRS-2002 and quality of life scales were applied, and biochemical parameters were recorded.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
| Nutrition, Healthy | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Active Comparator Group ( Standard enteral nutrition) | Dietary Supplement | — | UNRESOLVED |
| Experimental (Immunonutrition) Group | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- immunonutrition (intervention group)
- description
- Immunonutrition enteral products was given to the patients in the intervention group
- interventionNames
- Dietary Supplement: Experimental (Immunonutrition) Group
- type
- ACTIVE_COMPARATOR
- label
- standard (control group)
- description
- Standard enteral products was given to patients in the control group.
- interventionNames
- Dietary Supplement: Active Comparator Group ( Standard enteral nutrition)
Primary outcomes (10)
- measure
- Body weight
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Clinical diagnosis of squamous cell carcinoma of the oral cavity, oropharynx, larynx or hypopharynx who will undergo surgery, * who agree to receive standard EN or immunonutrition before surgery, * those between the ages of 18-75, * those with normal hematopoietic (absolute neutrophil count \>1.8x109/L, hemoglobin level ≥9 g/dL) hepatic and renal function Exclusion Criteria: * Patients receiving neoadjuvant chemotherapy or radiotherapy to the head and neck region; * Received EN support before the study * have an active infection, any autoimmune, renal or hepatic disease, malabsorption, type 1 diabetes or mental illness * taking vitamin-mineral supplements and immunosuppressive treatment, * Morbidly obese (BMI ≥40 kg/m2), HIV positive, pregnant and breastfeeding individuals
References
Publications (0)
Data not yet available