Clinical trial · Observational
Outcomes Comparison Between Bone Resection and Subperiosteal Dissection for Specific Type of Soft Tissue Sarcoma
Does Composite Bone Resection for Soft Tissue Sarcoma With Cortical Contact Result in Better Local Control and Survival Compared to Sub-periosteal Dissection?
NCT06317480CI-TRIAL-00075173completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
the purpose of this study is to assess whether bone resection for thigh soft tissue sarcoma with cortical involvement of the adjacent bone result in better local control and survival compared to sub-periosteal dissection. Investigators also aim to find out the prognostic factors for clinical outcomes in this group of patients.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cortical Contact | — | UNRESOLVED | — |
| Soft Tissue Sarcoma | Soft Tissue Sarcoma | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| bone resection | Procedure | — | UNRESOLVED |
| subperiosteal excision | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- bone resection
- interventionNames
- Procedure: bone resection
- label
- subperiosteal excision
- interventionNames
- Procedure: subperiosteal excision
Primary outcomes (3)
- measure
- survival
- timeFrame
- patients were checked every three months for the initial two years after surgery and every 6 months for the subsequent three years. After 5 years, patients will be checked once every year until patients died or were loss to follow up.
- description
- Whether patient die or not
- measure
- recurrence
- timeFrame
- patients were checked every three months for the initial two years after surgery and every 6 months for the subsequent three years. After 5 years, patients will be checked once every year until patients died or were oss to follow up.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 8 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients developed thigh soft tissue sarcoma, defined as lesion located below the plane of the lesser trochanter and above the plane of the femoral condyle. 2. received primary limb-salvage surgery at our center. 3. soft tissue sarcoma with only cortical contact of the adjacent bone based on preoperative imaging 4. minimum of 2-year follow up Exclusion Criteria: 1. diagnosis was well differentiated liposarcoma 2. patients with metastatic disease at the time of presentation 3. soft tissue sarcoma displayed frank osseous invasion (eg. medullary canal invasion)
References
Publications (0)
Data not yet available
No reference posted for this study.