Clinical trial · Interventional
Comparison of Spinal Anesthesia and Spermatic Cord Block for Bilateral Orchiectomy
The Feasibility of Local Anesthesia for Bilateral Orchiectomy : a Randomized Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this randomized controlled trial is to compare intraoperative pain score, Morphine consumption during 6 and 12 hour after surgery, and postoperative complications between SA and SCB groups in metastatic prostate cancer patient. The main question it aims to answer are: • Is there a difference in the level of pain during bilateral orchiectomy between spinal anesthesia and spermatic cord block? Participants will undergo bilateral orchidectomy. They will be randomly assigned to two groups: the group receiving spinal anesthesia and the group receiving spermatic cord block If there is a comparison group: Researchers will compare intraoperative pain score, Morphine consumption during 6 and 12 hour after surgery, and postoperative complications in both groups of patients.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Orchiectomy | — | UNRESOLVED | — |
| Pain Score | — | UNRESOLVED | — |
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
| Spermatic Cord Block | — | UNRESOLVED | — |
| Spinal Anesthesia | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| bilateral orchiectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Spinal anesthesia
- description
- spinal anesthesia : 0.5%hyperbaric bupivacaine 10-15 mg/dose injected at L3-L5
- interventionNames
- Procedure: bilateral orchiectomy
- type
- EXPERIMENTAL
- label
- spermatic cord block
- description
- 1%Xylocaine with adrenaline (Max 7 mg/kg/dose) divided to inject into each side of the spermatic cord 6-8 ml and infiltration into the scrotal incision area 3-4 ml.
- interventionNames
- Procedure: bilateral orchiectomy
Primary outcomes (1)
- measure
- intraoperative pain score
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- Male
Show eligibility criteria text
Inclusion Criteria: * Patients of all ages diagnosed with prostate cancer undergoing treatment with bilateral orchiectomy Exclusion Criteria: 1. Patients with a history of Xylocaine allergy. 2. Patients with uncorrected bleeding disorders. 3. Patients with paralysis or neurosensory deficits 4. Patients with dementia or cerebrovascular accidents (strokes) that impair communication. 5. Patients with contraindications for epidural anesthesia, including: * Patient refusal of spinal anesthesia. * Infection at the site of spinal injection. * Allergy to specific types of local anesthetics, such as Hyperbaric bupivacaine. * Inability of the patient to cooperate with the spinal anethetic procedure. * Suspicion of high intracranial pressure based on abnormal physical examination. * Aortic stenosis with fixed cardiac output. * Low platelet count.
References
Publications (0)
Data not yet available