Clinical trial · Observational
Cardio-Oncology Rehabilitation Care Process
Hospital-based Cardio-Oncology Rehabilitation Care Process for Cardiovascular Health in Cancer Patients
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The objective of this observational study is to assess the outcomes of a hospital-based Cardio-Oncology Rehabilitation (CORe) program focused on exercise in cancer patients undergoing cardiotoxic treatment. This evaluation will be conducted by analyzing disease-related health indicators, functional capacity, and quality of life. Patients at risk of cardiotoxicity attending the Cardio-Onco-Hematology Unit will be offered the exercise program, which includes two modalities: in-person (center-based) and remote (home-based) options. The assignment to either modality is non randomized, based on the functional assessment conducted in the Rehabilitation Unit and the agreement between healthcare professional and patient. All participants will perform a 3-month supervised exercise intervention. There are 3 time points for assessment: at baseline (T0), 3-month after the exercise program (T1) and follow-up at 9 months from baseline (T2).
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cardio-Oncology | — | UNRESOLVED | — |
| Cardiovascular Diseases | — | UNRESOLVED | — |
| Exercise | — | UNRESOLVED | — |
| Rehabilitation | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Exercise-based cardio-oncology rehabilitation | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Center-Based Cardio-Oncology Rehabilitation (CBCORe)
- description
- Therapeutic exercise program supervised by a physiotherapist. 2 days/week, duration 1h, in the Cardiac Rehabilitation ward.
- interventionNames
- Other: Exercise-based cardio-oncology rehabilitation
- label
- Home-Based Cardio-Oncology Rehabilitation (HBCORe)
- description
- Recommendation of physical exercise and motivational interview through telephone follow-up every 2 weeks by the physiotherapist.
- interventionNames
- Other: Exercise-based cardio-oncology rehabilitation
Primary outcomes (8)
- measure
- Change in left ventricular systolic function quantified by left ventricular ejection fraction and global longitudinal strain by transthoracic echocardiography
- timeFrame
- Baseline (T0); 3 months after completing the exercise program (T1); follow-up at 9 months from baseline (T2); every year after study completion up to a maximum of 5 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * High risk of cancer treatment-related cardiotoxicity * Possibility of completing a cardio-onco rehabilitation program (centre-based or home-based) and programmed visits. * Providing written informed consent. Exclusion Criteria: * Patients with physical or mental limitation to carry out an exercise program.
References
Publications (0)
Data not yet available