Clinical trial · Observational
Spatial Profile of Tumors
SPATIAL PROFILE OF SUBPOPULATIONS OF CANCER AND IMMUNITARY CELLS IN SEVERAL SOLID TUMORS
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The research project focuses on analyzing the spatial organization of cells within various solid tumors, utilizing advanced technologies enabling in-depth multi-parametric analysis of tumor and immune cells. The primary objective is to understand the spatial distribution of cellular subpopulations within each type of tumor, while secondary objectives include correlating these data with clinical aspects and identifying potential therapeutic targets. The study involves 1000 patients with primary or metastatic tumors and spans a duration of 5 years, from 2024 to 2028. No experimental treatments are planned; rather, only spatial imaging analyses with multiple markers will be conducted. Data analysis involves descriptive statistical methods and hypothesis testing to generate hypotheses for subsequent studies. The analyses will be performed using SPSS® version 21.0 software for Windows®.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Solid Tumors | Solid Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Spatial analysis of paraffin samples from solid tumors | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Spatial analysis of cancer cells
- timeFrame
- 7 days
- description
- Spatial distribution analysis of the main cell subpopulations characterising the tumours studied.
Secondary outcomes (2)
- measure
- Comparison of clinical data
- timeFrame
- 1 day
- description
- Correlation of spatial analysis data with patient clinical data
- measure
- Identification of therapeutic targets
- timeFrame
- 4 weeks
- description
- Identification of possible therapeutic targets of different subpopulations
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * male or female subjects aged 18 years * primary or metastatic tumors Diagnosed by histology and/or radiological evidence, RNM, or endoscopic * signature of informed consent * substitute declaration to the consent form where applicable Exclusion Criteria: * previous unrelated tumour disease * significant acute or chronic infections (HIV, HCV and HBV infections) and/or ongoing bacterial and viral infections * active autoimmune disease * pregnant or breastfeeding * patients who do not sign informed consent
References
Publications (0)
Data not yet available