Clinical trial · Interventional
Efficacy of Olanzapine on Weight Gain in Advanced Gynecologic Cancer with Paclitaxel and Carboplatin: a Double Blind, Placebo-controlled Randomized Trial
Efficacy of Olanzapine on Weight Gain in Women with Advanced Stage Gynecologic Cancer Receiving Paclitaxel and Carboplatin Combination Chemotherapy : a Double Blind, Placebo-controlled Randomized Trial
NCT06288854CI-TRIAL-00082881unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
* Efficacy of olanzapine on weight gain in advanced stage gynecologic cancer * Proprotion of pateints in advanced stage gynecologic cancer who recieving paclitaxel and carboplatin chemotherapy gain weight on olanzapine or placebo
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Weight Gain | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| weight gain each group | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Olanzapine
- description
- Olanzapine 5 mg oral OD
- interventionNames
- Other: weight gain each group
- type
- PLACEBO_COMPARATOR
- label
- Placebo
- description
- Placebo
- interventionNames
- Other: weight gain each group
Primary outcomes (1)
- measure
- Efficacy of olanzapine on weight gain in advanzed stage gynecologic cancer recieving paclitexal and carboplatin chemotherapy
- timeFrame
- 12 weeks after intervention
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Advanced stage gynecologic cancer receiving Paclitaxel and carboplatin chemotherapy * ECOG 0-1 * Normal CBC,Liver, renal function * Communication in Thai language or Thai caregiver * Inform consent Exclusion Criteria: * Pregnancy * Active infection * Bowel obstruction or history of bowel surgery * On dopamine receptor antagonists or psychiatric or anticonvulsant medication * Olanzapine allery * Abnormal function of liver and renal * Diabetic melitus or morbid obesity * patient can't selfcare
References
Publications (0)
Data not yet available
No reference posted for this study.