Clinical trial · Interventional
Cervical Cancer Brachytherapy With Interstitial Needles in 3 Fractions
Cervical Cancer Brachytherapy With Interstitial Needles in 3 Fractions: Dosimetric and Clinical Outcomes
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Aim To determine the feasibility and safety of 3 fractions of high dose rate (HDR) brachytherapy with interstitial needles for cervical cancer in the outpatient setting Primary objective To determine the clinical outcome (2-yr local control rate, loco-regional control rate, progression free survival and overall survival) Secondary objective To determine the long-term toxicities of this regimen based on CTCAE v5
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cervical Cancer | Malignant Cervical Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 3 fractions HDR brachytherapy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- 3 fractions
- interventionNames
- Procedure: 3 fractions HDR brachytherapy
Primary outcomes (4)
- measure
- Local control rate
- timeFrame
- 2 years from time of recruitment
- description
- Percentage of patients who recurred at the site of the initial primary (the cervix).
- measure
- Loco-regional control rate
- timeFrame
- 2 years from time of recruitment
- description
- Percentage of patients who recurred in the pelvis or regional lymph nodes (not in cervix).
- measure
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria: 1. 21 years old and above 2. Histologically proven squamous cell carcinoma, adenocarcinoma, adenosquamous or poorly differentiated cervical cancer 3. Clinically or radiologically stage IB - IVA cervical cancer based on TNM 8th Edition 4. ECOG performance status 0, 1, or 2 5. To complete external beam radiotherapy and brachytherapy in NUH 6. Written, voluntary informed consent 7. Patients must be accessible for follow up and management in NUH Exclusion Criteria: 1. Post operative cervical cancer cases 2. Pregnant or breastfeeding women
References
Publications (0)
Data not yet available