Clinical trial · Observational
Postoperative Morbidity and Mortality After Gastric Cancer Surgery
90-day Postoperative Morbidity and Mortality After Elective Surgery for Gastric Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Gastric cancer is still one of the main health care issue and gastrectomy with lymph node dissection is the only chance to be cure. Trials show that the postoperative course differs significantly between eastern and western centers, as well as between clinics within Russian Federation. Postoperative 30-day postoperative mortality after gastric cancer surgery ranges from 1% to 5%, and postoperative complication rates range from 10% to 40%. To improve the quality of further studies and recommendations for standardization of surgical treatment of gastric cancer and its complications, there is a need to study the differences in 90-day postoperative morbidity and mortality in different clinics and centers of the Russian Federation.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
| Siewert Type III Adenocarcinoma of Esophagogastric Junction | Gastric Neoplasm | PROBABILISTIC | 0.70 |
| Stomach Cancer | Malignant Gastric Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Elective Surgery for gastric cancer | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Patients with morbidity
- description
- Patients who suffered from any type of morbidity after surgery
- interventionNames
- Procedure: Elective Surgery for gastric cancer
- label
- Patients without morbidity
- description
- Patients who did not suffer from any type of morbidity after surgery
- interventionNames
- Procedure: Elective Surgery for gastric cancer
Primary outcomes (1)
- measure
- the type of complications and the incidence of it
- timeFrame
- within 90 days after operation
- description
- the types of complication is classified into as follows: anastomotic leak, postoperative bleeding requiring invasive treatment, other complications requiring re-intervention or other invasive procedure, postoperative bowel obstruction, postoperative pancreatic fistula, duodenal leak, gastrostasis, postoperative pancreatitis, postoperative bowel perforation or necrosis, non-surgical infections, pleural effusion requiring drainage, respiratory failure requiring reintubation, acute renal failure requiring hemofiltration/dialysis, need for prolonged intubation, need for tracheostomy, need for cardiopulmonary resuscitation, pulmonary embolism, pneumothorax requiring treatment, myocardial infarction, acute myocardial failure, cardiac dysrhythmia requiring invasive treatment, stroke, acute liver dysfunction, other complications. Each complication will be graded according to Clavien-Dindo classification. Re-admission or visiting emergency room will be checked and recorded.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: All consecutive patients with primary gastric malignancy (including Siewert III) undergoing elective surgery with curative intent (either total or partial gastrectomy) via open, laparoscopic or robotic approach between 18th March 2024 and 18th September 2024. Exclusion Criteria: * Patients with clinical evidence of metastatic disease, including positive peritoneal cytology on previous staging laparoscopy, * Patients with known synchronous cancer; * Patients with Gastrointestinal stromal tumors (GIST) * Presence of gastroesophageal junction (Siewert I and II) malignancy; * Patients submitted to Emergency surgery or surgery without curative intent; * Patients undergoing additional surgery (except cholecystectomy) along with surgery for gastric cancer.
References
Publications (0)
Data not yet available