Clinical trial · Interventional
Topical Anaesthesia in Cutaneous Head and Neck Surgery
Topical Anaesthesia in Cutaneous Head and Neck Surgery: a Randomized Controlled Trial
NCT06274905CI-TRIAL-00074305completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims to assess if EMLA or ethyl chloride spray are effective in reducing the pain associated with local anaesthetic administration in cutaneous surgery of the head and neck compared to a placebo and control group through a randomized control trial study design.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cutaneous Tumor | — | UNRESOLVED | — |
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
| Pain, Acute | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Aqueous cream BP | Drug | — | UNRESOLVED |
| EMLA | Drug | — | UNRESOLVED |
| Ethyl chloride | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- EXPERIMENTAL
- label
- EMLA cream
- description
- EMLA cream 5% 25g lidocaine, 25g prilocaine; Astra Zeneca. Topically applied followed by Tegaderm dressing to cover. Length of duration monitored and recorded as part of study
- interventionNames
- Drug: EMLA
- type
- PLACEBO_COMPARATOR
- label
- EMLA placebo
- description
- Aqueous cream ((Ultrapure Laboratories®️, Mayo, Ireland) applied topically followed by covering with Tegaderm dressing. Length of duration monitored and recorded as part of study
- interventionNames
- Drug: Aqueous cream BP
- type
- EXPERIMENTAL
- label
- Ethyl chloride spray
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Aged at least 18 years * Receiving surgery to cutaneous tissues of the head and neck * Procedure performed under local anaesthetic Exclusion Criteria: * Paediatric patients * Surgery performed under general anaesthetic * Mucosal operative site (e.g. oral cavity) * Significant cognitive impairment (e.g. severe dementia) * Known sensitivity/allergy to EMLA * History of a pain disorder (e.g. complex regional pain syndrome).
References
Publications (0)
Data not yet available
No reference posted for this study.