Clinical trial · Interventional
Effects of Exercise Training in Survivors of Lymphoma
The LYMfit Study: Exercise Training to Prevent Cardiovascular Disease in Lymphoma Survivors
NCT06270667CI-TRIAL-00075307LYMfitrecruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims to compare the effects of aerobic exercise with or without addition of resistance exercise to usual care in individuals treated with anthracyclines for lymphomas and to compare exercise effects to age- and sex-matched individuals with no prior history of malignant diseases.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cardiotoxicity | — | UNRESOLVED | — |
| Cardiovascular Diseases | — | UNRESOLVED | — |
| Chemotherapeutic Toxicity | — | UNRESOLVED | — |
| Lymphoma | Lymphoma | ONTOLOGY_EXACT | 0.90 |
| Physical Exercise | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Aerobic Exercise | Behavioral | — | UNRESOLVED |
| Combined Aerobic and Resistance Exercise | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- EXPERIMENTAL
- label
- Aerobic Exercise
- description
- Aerobic Exercise twice weekly for 5 months.
- interventionNames
- Behavioral: Aerobic Exercise
- type
- EXPERIMENTAL
- label
- Combined Aerobic and Resistance Exercise
- description
- Combined Aerobic and Resistance Exercise twice weekly for 5 months.
- interventionNames
- Behavioral: Combined Aerobic and Resistance Exercise
- type
- NO_INTERVENTION
- label
- Standard Care
- description
- Standard Care, i.e no exercise intervention.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria Lymphoma participants: * Listed in relevant registers * Confirmed lymphoma diagnosis (i.e., Hodgkin lymphoma and aggressive non-Hodgkin lymphoma) * Completed treatment in the past two to five years without relapse or second cancer * Previous anthracycline treatment with or without mediastinal radiation * No severe cancer-related fatigue (per self-report) Inclusion Criteria Lymphoma participants and non-cancer reference group: * Currently not performing \>75 minutes/week of aerobic exercise * Willing and able to adhere to all study procedures. Exclusion Criteria Lymphoma participants: * Relapse since diagnosis * A history, or current presence, of another diagnosis of invasive cancer of any kind Exclusion Criteria Lymphoma participants and non-cancer reference group: * Presence of any uncontrolled- or recent cardiovascular disease * Has undergone heart surgery * Uses a pacemaker * Pregnancy * Unable to read and understand Swedish (applicable for the Swedish site only) * Unable to read and understand Norwegian (applicable for the Norwegian site) * Any physical or mental health condition restricting adherence to study protocol
References
Publications (0)
Data not yet available
No reference posted for this study.