Clinical trial · Interventional
Feasibility of a Preoperative, Multimodal Lifestyle Intervention in Patients With Breastcancer
FeAsibility of a PReoperative, Multimodal Lifestyle InterventiOn in Patients With Breast Cancer ReceivIng Neoadjuvant Chemotherapy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The primary objective of this study is to investigate the feasibility of a multimodal prehabilitation programme consisting of MIET during neoadjuvant intravenous chemotherapy infusion, HITT and strength training during the last six weeks prior to surgery, and optimising nutritional intake throughout the total preoperative period in patients with breast cancer with respect to recruitment, adherence, dropout, safety and acceptance. The secondary objective is to provide a preliminary evaluation of participant responses to a preoperative multimodal lifestyle intervention, on cardiorespiratory fitness, muscle strength, nutritional status, and fatigue in patients with breast cancer receiving neoadjuvant chemotherapy.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Breast Neoplasms | Breast Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| A multimodal prehabilitation programme | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- multimodal lifestyle intervention
- description
- A group receiving a multimodal prehabilitation programme consisting of three modalities: 1. MIET during neoadjuvant intravenous chemotherapy infusion 2. HITT and strength training during the last six weeks prior to surgery 3. Optimising nutritional intake throughout the total preoperative period
- interventionNames
- Behavioral: A multimodal prehabilitation programme
Primary outcomes (20)
- measure
- Recruitment rate (%)
- timeFrame
- Week 0
- description
- Number of included patients / number of eligible patients within the study period
- measure
- Characteristics of included participants
- timeFrame
- Week 0
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients diagnosed with stage I-III breast cancer eligible for neoadjuvant intravenous chemotherapy at the MUMC+ * Aged ≥18 years * Eastern Cooperative Oncology Group (ECOG) Performance Status Scale grade 0-1 (Table 1) * Enough understanding of the Dutch language Exclusion Criteria: * Human Epidermal growth factor Receptor 2 (HER2) - positive tumour * Scalp cooling * Conditions that seriously hamper physical exercise * Incapacitated subjects as reported by the attending medical specialist in the medical record. When any doubt arises, the patient will not be considered eligible.
References
Publications (0)
Data not yet available