Clinical trial · Observational
Magnetic Localization of Sentinel Nodes in Squamous Cell Oral Carcinoma.
Diagnostic Value of Sentinel Node Biopsy Guided by Magnetic Probe in Squamous Cell Oral Carcinoma: a Prospective Observational Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Sentinel node biopsy has been shown to be a viable alternative to elective neck dissection in the early stages of squamous cell oral carcinoma. The aim of this study was to describe the magnetic localization of sentinel nodes (SN) after peritumoral injection of superparamagnetic iron oxide (SPIO) for treating this type of tumor and to analyze the technique's diagnostic performance in 23 patients. The technique located SNs (with minimal complication) in 95.6 % (22/23) of the patients. Three relapses occurred, one in a patient who had shown negative in magnetic SN location and elective neck dissection. The diagnostic performance of magnetic localization achieved a sensitivity and negative predictive value of 0.80 y 0.94, respectively. Magnetic localization of SNs has been shown to be a reproducible technique that may offer a viable alternative to the conventional technique.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Diagnostic Value of Sentinel Node Biopsy Guided by Magnetic Probe | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Sentinel node biopsy guided by magnetic probe | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Patients diagnosed with oral squamous cell carcinoma at stages I-II
- description
- The patients underwent sentinel node biopsy and posterior neck dissection
- interventionNames
- Procedure: Sentinel node biopsy guided by magnetic probe
Primary outcomes (1)
- measure
- The diagnostic performance of SNB was analyzed in terms of sensitivity (S), specificity (Sp), negative and positive predictive value (NPV and PPV).
- timeFrame
- Six years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 29 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: * Oral squamous cell carcinoma T1-T2, cN0. * Absence of alterations to iron metabolism. Exclusion Criteria: * Previous neck surgery. * Treatment with iron chelators. * Pregnant
References
Publications (0)
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