Clinical trial · Interventional
Stapler Versus Conventional Pharyngeal Repair After Total Larygectomy
Linear Stapler Versus Conventional Repair of the Pharynx After Total Laryngectomy: Functional and Oncological Outcomes
NCT06256263CI-TRIAL-00073953completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study was done to investigate the efficacy and safety of the linear stapler closure of the pharynx after total laryngectomy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Malignant Tumor of the Larynx | Malignant Laryngeal Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| total laryngectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- stapler repair group
- description
- pharyngeal repair after total laryngectomy was done by using a linear stapler
- interventionNames
- Procedure: total laryngectomy
- type
- ACTIVE_COMPARATOR
- label
- conventional repair group
- description
- pharyngeal repair after total laryngectomy was done by the conventional method (stitching).
- interventionNames
- Procedure: total laryngectomy
Primary outcomes (1)
- measure
- incidence of pharyngocutaneous fistula after total laryngectomy
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * All consecutive patients undergoing total laryngectomy for advanced laryngeal carcinoma in the study duration . Exclusion Criteria: * Infiltration of the safety margins proved by postoperative histopathology . * Patients with tumor extension to the tongue base, or the hypopharynx . * Patients who are unfit for surgery . * Patients refusal to surgical treatment
References
Publications (3)
- BACKGROUNDSansa-Perna A, Casasayas-Plass M, Rovira-Martinez C, Lopez-Vilas M, Garcia-Lorenzo J, Quer-Agusti M, Leon-Vintro X. Pharyngeal closure after a total laryngectomy: mechanical versus manual technique. J Laryngol Otol. 2020 Jul;134(7):626-631. doi: 10.1017/S0022215120001371. Epub 2020 Jul 29. PMID 32723416
- BACKGROUNDSannikorn P, Pornniwes N. Comparison of outcomes for staple and conventional closure of the pharynx following total laryngectomy. J Med Assoc Thai. 2013 Mar;96 Suppl 3:S89-93. PMID 23682529
- BACKGROUNDShan H, Gao Y, Liu L, Li M, Gao X, Li Y, Wang X, Ouyang D, Guo Z. Magnifying endoscopy with narrow-band imaging to assist the linear stapler closure of the pharynx during total laryngectomy. Am J Otolaryngol. 2018 Sep-Oct;39(5):511-514. doi: 10.1016/j.amjoto.2018.05.014. Epub 2018 May 28. PMID 29903625