Clinical trial · Interventional
The PRISM-Social Needs (PRISM-SN) Intervention for Adolescents and Young Adults With Cancer
The Promoting Resilience in Stress Management-Social Needs (PRISM-SN) Intervention for Adolescents and Young Adults With Cancer: A Randomized Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 10, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260910-000001
Summary
Brief summary (as posted)
The goal of this study is to establish feasibility, acceptability, and proof-of-concept of an psychosocial intervention adapted to address social health needs of adolescents and young adults (AYAs) newly diagnosed with cancer. The aims of this study are to: 1. Determine if the Promoting Resilience in Stress Management - Social Needs (PRISM-SN) adapted intervention is feasible and acceptable, defined via program uptake and retention and patient-reported feedback. 2. Explore whether PRISM-SN improves social outcomes at 12-week follow-up compared to usual care. Participants will be randomized to receive usual psychosocial care or the PRISM-SN program. Participants on both arms will complete patient-reported outcome surveys at enrollment and 12-weeks later. Researchers will compare participants who received the PRISM-SN program to those who received usual care to see if the program improves psychosocial outcomes.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Coping Skills | — | UNRESOLVED | — |
| Psychosocial Functioning | — | UNRESOLVED | — |
| Social Functioning | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Promoting Resilience in Stress Management - Social Needs (PRISM-SN) | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- PRISM-SN Intervention
- description
- Skill-based psychosocial program
- interventionNames
- Behavioral: Promoting Resilience in Stress Management - Social Needs (PRISM-SN)
- type
- NO_INTERVENTION
- label
- Usual Care
- description
- Standard psychosocial care
Primary outcomes (1)
- measure
- Cancer Behavior Inventory - Social Relationship Coping Efficacy (CBI-SCRE) Measure
- timeFrame
- 12-weeks
- description
- The Cancer Behavior Inventory - Social Relationship Coping Efficacy measure assesses one's confidence to engage in behaviors that maintain or enhance close social relationships in the context of illness. Ten items are rated 1-10; items are summed, with higher scores reflecting higher social relationship coping efficacy.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 12 Years
- Maximum age
- 25 Years
Show eligibility criteria text
Inclusion Criteria: * Aged 12-25 years * Diagnosed with new malignancy treated with chemotherapy and/or radiation \<6-months * Able to speak in the English language * Able to read in the English language * Cognitively able to participate in intervention sessions and complete surveys Exclusion Criteria: * Aged \<12 or \>25 years * Diagnosed with recurrent malignancy * Diagnosed with new malignancy \>6 months * Not receiving chemotherapy and/or radiation * Not able to speak in the English language * Not able to read in the English language * Not cognitively able to participate in intervention session or complete surveys
References
Publications (1)
- DERIVEDFladeboe KM, Fredman G, Maurer SH, Zhou C, Bradford MC, Yi-Frazier JP, Salsman JM, Baker KS, Mack MC, Taylor MR, Rosenberg AR. Feasibility and proof-of-concept of a combined resilience and social connection intervention for adolescents and young adults with cancer: a pilot randomized trial protocol. Pilot Feasibility Stud. 2026 Jan 29;12(1):32. doi: 10.1186/s40814-026-01775-0. PMID 41612517