Clinical trial · Interventional
Generation of Lung Tumor Organoids From Patients Undergoing Diagnostic Bronchoscopy
NCT06239584CI-TRIAL-00073592unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Interventional (low intervention level), non-pharmacological, prospective, feasibility pilot study of the preparation of organoids starting from lung tumor tissue collected during biopsies performed via diagnostic bronchoscopy according to standard clinical practice.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Generation of Lung Cancer Organoids | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Biopsies performed via bronchoscopy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Patients undergoing diagnostic bronchoscopies for suspected lung cancer
- description
- Preparation of organoids starting from lung tumor tissue collected during biopsies performed via diagnostic bronchoscopy according to standard clinical practice
- interventionNames
- Procedure: Biopsies performed via bronchoscopy
Primary outcomes (1)
- measure
- Preparation of at least 10 tumor organoid cultures lung
- timeFrame
- 12 months
- description
- Preparation of at least 10 tumor organoid cultures lung derived from patients undergoing diagnostic bronchoscopy. This study will allow define the success rate in the generation of organoids from diagnostic bronchoscopies. Performing a diagnostic bronchoscopy (scheduled as per clinical practice).
Secondary outcomes (1)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * patients with suspected diagnosis of centrally located and accessible lung cancer endoscopically; * patients for whom it is indicated to undergo in-depth diagnostic testing through bronchoscopy for the purpose of determining the histotype of the lung neoplasm, according to clinical practice standard; * aged over 18; * patients who express informed consent to the study. Exclusion Criteria: * medical contraindication to taking biopsy samples; * medical contraindication to carrying out endoscopic investigations; * patients with suspected lung cancer not accessible endoscopically; * patients with lung neoformation already subjected to diagnostic sampling; * contraindications to taking an additional quantity of tissue.
References
Publications (0)
Data not yet available
No reference posted for this study.