Clinical trial · Interventional
Aerobic Dance During Chemotherapy in Breast Cancer Patients With Cognitive Impairment
Aerobic Dance During Chemotherapy in Breast Cancer Patients With Cognitive Impairment（ADANC）
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this clinical trial is to learn about breast cancer patients. The main questions it aims to answer are: * Does Aerobic Dance During Chemotherapy Improve Cognitive Function in Breast Cancer Patients？ * Does the efficacy of aerobic dance differ from fast walking of equal intensity？ Recruited patients will be randomly assigned to three groups: (1) aerobic dance group, (2) fast walking group, and (3) usual care group. The aerobic dance and fast-walking groups participated in supervised exercise lasting 50 minutes thrice a week for 12 weeks. The goal of this study's findings is to develop practical strategies for managing breast cancer-related cognitive impairment.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Neoplasms | Breast Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Chemotherapy-Related Cognitive Impairment | — | UNRESOLVED | — |
| Cognitive Dysfunction | — | UNRESOLVED | — |
| Dance Therapy | — | UNRESOLVED | — |
| Exercise Therapy | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Aerobic dance | Other | — | UNRESOLVED |
| Fast-walking | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Aerobic dance
- description
- 50 minutes of moderate-intensity aerobic dance three times a week
- interventionNames
- Other: Aerobic dance
- type
- EXPERIMENTAL
- label
- Fast-walking
- description
- 50 minutes of moderate-intensity fast walking three times a week
- interventionNames
- Other: Fast-walking
- type
- NO_INTERVENTION
- label
- Usual care
- description
- Maintain the usual lifestyle and receive medical treatment as normal as the rest of the group.After the baseline evaluation, participants in the control group are asked to maintain their regular lifestyle, including their level of physical activity, and to continue receiving medical treatment and care by standard procedures for 12 weeks. The control group did not receive any encouragement from the researcher to increase the time they spent exercising because, at the time of patient data collection, they were not routinely informed about the benefits of exercise during chemotherapy. Control patients were allowed to engage in the same experimental exercise condition after the 24-week study cycles; if they declined, the study would be stopped.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * 18-65 years old * Newly diagnosed, histologically confirmed, resected stage I-IIIa BC * Scheduled for chemotherapy with Epirubicin+ Cyclophosphamide (EC) regimen * Presence of objective cognitive decline Exclusion Criteria: * Regular exercise habits (exercise at moderate intensity for 30 minutes a day, 3 days a week, for at least 3 months.), * Motor dysfunction * Alzheimer's disease * Vascular dementia
References
Publications (1)
- DERIVEDCheng Y, Xu L, Xia N, Wang J, Yang W, Jin C, Wang R, Qin J, Zhu Y. Aerobic dance during chemotherapy in patients with breast cancer with cognitive impairment (ADANC): protocol for an assessor-blinded randomised clinical trial. BMJ Open. 2025 Oct 17;15(10):e092003. doi: 10.1136/bmjopen-2024-092003. PMID 41106863