Clinical trial · Interventional
Digital Home-Based Prehabilitation Before Surgery
NCT06231576CI-TRIAL-00073404dHOPEnot yet recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This clinical trial compares two different prehabilitation programs, with no organized prehabilitation, prior to major colorectal cancer surgery. The prehabilitation programs include intensive and coached physical exercise and optimized nutritional intake coupled with smoking cessation, physiological support and correction of poly-pharmacy.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer Colorectal | — | UNRESOLVED | — |
| Frailty | — | UNRESOLVED | — |
| Surgery | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Prehabilitation | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Hospital
- description
- Prehabilitation at the hospital, with guidance by a dedicated physiotherapist physically present.
- interventionNames
- Other: Prehabilitation
- type
- EXPERIMENTAL
- label
- Digital
- description
- Prehabilitation at home, with guidance from a dedicated physiotherapist through a digital platform, realtime.
- interventionNames
- Other: Prehabilitation
- type
- NO_INTERVENTION
- label
- Control
- description
- Information about the general benefit of a healthy lifestyle at inclusion, thereafter no further follow-up prior to surgery.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Planned for major gastrointestinal cancer surgery * Fluent in Norwegian and able to consent and to understand questionnaires Exclusion Criteria: * Inability to walk for six minutes or to rise independently from a chair * Inability to comprehend exercise program or to comply with written and oral instructions * Presence of a cardio-pulmonary condition that precludes exercise * Living in very remote areas making a hospital-based intervention group impossible to implement * Being without a permanent address * Admittance to a hospital facility for \> 50% of the time from diagnosis to surgery
References
Publications (1)
- DERIVEDKleve G, Santa CD, Kristiansen F, Tegnander M, Buch V, Hagemann CS, Helgheim M, Engene P, Pesonen H, Kleveland MK, Hverven GL, Nilsen TS, Vervaart MAM, Aanesen H, Uglane KT, Bjelland M, Zory R, Chorin F, Cardot-Ruffino V, Beltran EEM, Neuzillet C, Soerensen M, Jylhava J, Anzar I, Normand VA, Myrstad M, Klungland A, Nilsen HL, Ougland R. Digital home-based multimodal prehabilitation of colorectal cancer patients prior to surgery (the dHOPE study): a non-inferiority clinical trial protocol. Front Digit Health. 2025 Oct 8;7:1609678. doi: 10.3389/fdgth.2025.1609678. eCollection 2025. PMID 41132395