Clinical trial · Interventional
A Prospective Trial Comparing Transoral Endoscopic Thyroidectomy Vestibular Approach (TOETVA) and Conventional Open Thyroidectomy
NCT06225765CI-TRIAL-00078645recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To determine if transoral endoscopic thyroidectomy vestibular approach (TOETVA) is a safe and effective procedure compared to traditional open thyroidectomy. Surgical outcomes, patients' satisfaction, voice and swallowing outcomes will be assessed.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Benign Thyroid Nodule | — | UNRESOLVED | — |
| Suspicious Malignant Thyroid Nodule | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Traditional Open Thyroidectomy | Procedure | — | UNRESOLVED |
| Transoral endoscopic thyroidectomy vestibular approach (TOETVA) | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Transoral endoscopic thyroidectomy vestibular approach (TOETVA)
- description
- Test group receiving surgery under transoral endoscopic thyroidectomy vestibular approach (TOETVA)
- interventionNames
- Procedure: Transoral endoscopic thyroidectomy vestibular approach (TOETVA)
- type
- ACTIVE_COMPARATOR
- label
- Traditional open surgery
- description
- Control group receiving traditional open thyroidectomy
- interventionNames
- Procedure: Traditional Open Thyroidectomy
Primary outcomes (14)
- measure
- Patient's satisfactory score
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Benign thyroid nodule less than 4cm * Suspicious malignant thyroid nodule less than 2cm, suitable for transoral endoscopic surgery Exclusion Criteria: * Patients under 18 years old * Contraindication to general anaesthesia * Vulnerable population (e.g. Cognitive impairment, pregnant) * Previous anterior neck surgery * Previous radiotherapy at the head and neck region * Malignant thyroid nodule \> 2cm * Presence of another malignancy, lateral neck, or distant metastasis * Retrosternal goitre * Cervical spine disease precluding extension of the neck * Obesity with BMI \> 35kg/m2 * Severe concomitant illness that drastically shortens life expectancy or increases risk of therapeutic intervention * Untreated active infection * Non-correctable coagulopathy * Emergency surgery
References
Publications (0)
Data not yet available
No reference posted for this study.