Clinical trial · Observational
Predictors of Residual Tumor at Second Transurethral Resection for pT1 Non-muscle Invasive Bladder Cancer
NCT06205277CI-TRIAL-00072956STARTcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The START study is a multicentre retrospective project. The aim is to identify clinico-pathological predictors of residual tumor at time of second transurethral resection of bladder tumor (re-TURBt) and to identify well-selected candidates for a risk-adapted strategy in which this procedure could be safely spared.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bladder Cancer | Malignant Bladder Neoplasm | CURATED_EXACT | 0.92 |
| Non Muscle Invasive Bladder Cancer | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Second TURBt | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Patients with pT1 NMIBC who underwent second TURBt
- description
- Patients with pT1 NMIBC who underwent second TURBt after a macroscopically completede first TURBt within 6-8 weeks
- interventionNames
- Procedure: Second TURBt
Primary outcomes (1)
- measure
- Patients with histologically confirmed evidence of residual tumor at second TURBt
- timeFrame
- 6 to 8 weeks
- description
- Patients with histologically confirmed evidence of residual tumor at second TURBt defined as any pT BCa
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. patients undergoing second TURBt (re-TURBt) for pT1LG/HG NMIBC after a macroscopically completed first TURBt (in patients with multiple lesions only the index lesion pT1 conditioning the indication of re-TURBt will be considered). Therefore, presence of residual tumor or not at time of re-TURBt will be assessed at site of previous pT1. 2. patients able to provide written informed consent; 3. clinical-localized non-metastatic disease (cN0, cM0). Exclusion Criteria: 1. patients with clinical non-localized BCa (cN+, cM+); 2. patients with incomplete resection at time of first TURBt according to surgeon: macroscopic evidence of residual tumor, too long resection requiring a second-look will be excluded from the current study; 3. patients with incomplete clinical or demographic or pathological data; 4. patients who were unable to provide written informed consent; 5. patients who underwent urgency or emergency procedures in life-threating scenario
References
Publications (0)
Data not yet available
No reference posted for this study.