Clinical trial · Interventional
Effects of Aerobic Cycling Training in Patients With Gynecologic Cancer-related Lower Extremity Lymphedema
Effects of Aerobic Cycling Training in Patients With Gynecologic Cancer-related Lower Extremity Lymphedema: A Randomized Comparative Study
NCT06200948CI-TRIAL-00077441completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Comparison of complete decongestive treatment and complete decongestive treatment + cycling ergometry treatment in patients with gynecologic cancer-related lower extremity lymphedema in terms of quality of life, lower extremity functionality and lower extremity volume measurement
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gynecologic Cancer | Malignant Female Reproductive System Neoplasm | ALIAS | 0.90 |
| Lymphedema | — | UNRESOLVED | — |
| Lymphedema, Lower Limb | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Aerobic Exercise | Other | — | UNRESOLVED |
| Complete Decongestive Treatment | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- non-cycling group
- description
- patients will receive only complete decongestive treatment
- interventionNames
- Other: Complete Decongestive Treatment
- type
- ACTIVE_COMPARATOR
- label
- cycling group
- description
- patients will receive complete decongestive treatment + cycling ergometry treatment
- interventionNames
- Other: Aerobic Exercise
- Other: Complete Decongestive Treatment
Primary outcomes (1)
- measure
- Effect of Aerobic Training
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Being cognitively competent * Chemotherapy radiotherapy etc. treatment has been completed and there is no oncological risk * Signing written informed consent to participate in the study Exclusion Criteria: * Cardiac failure * Uncontrolled hypertension * Having kidney failure * Having a systemic infection * Local infection such as erysipelas and cellulitis in the lower extremities * Venous insufficiency (DVT etc.) * Presence of any neuromuscular disease affecting the lower extremities * Having lipolymphedema * Fracture in the lower extremity * Having active metastasis * Having a language problem * Being pregnant * Being unable to continue treatment
References
Publications (3)
- RESULTKendrova L, Mikulakova W, Urbanova K, Andrascikova S, Zultakova S, Takac P, Peresta Y. Comprehensive Decongestive Therapy as a Treatment for Secondary Lymphedema of the Lower Extremity and Quality of Life of Women After Gynecological Cancer Surgery. Med Sci Monit. 2020 Jun 17;26:e924071. doi: 10.12659/MSM.924071. PMID 32555125
- RESULTDionne A, Goulet S, Leone M, Comtois AS. Aquatic Exercise Training Outcomes on Functional Capacity, Quality of Life, and Lower Limb Lymphedema: Pilot Study. J Altern Complement Med. 2018 Sep/Oct;24(9-10):1007-1009. doi: 10.1089/acm.2018.0041. PMID 30247973
- DERIVEDKara O, Mete Civelek G, Sahbaz Pirincci C, Tarlabolen R, Dalyan M. Effects of aerobic cycling training in patients with gynaecologic cancer-related lower extremity lymphedema: A randomised comparative study. Support Care Cancer. 2025 Mar 19;33(4):302. doi: 10.1007/s00520-025-09354-4. PMID 40108020