Clinical trial · Observational
Research on the Accurate Diagnosis of Urinary Tract Tumors and the Development of Kits
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Bladder cancer is the second most prevalent urological malignancy worldwide, with a high incidence and poor patient prognosis. Achieving early diagnosis and intervention for bladder cancer is one of the most important ways to improve clinical management and patient prognosis. Tumor exosomes can be released into biological fluids at an early stage of a tumor, and many studies have shown that exosomal RNA can be used as a reliable biomarker to diagnose tumors in a non-invasive way. Based on the clinical needs for early diagnosis of bladder cancer, we aim to screen several early diagnostic markers with potential predictive value, establish an early diagnostic model for bladder cancer, and validate the validity and reliability of this diagnostic model through a large-scale clinical cohort to complement the diagnosis of early-stage cancers and to improve the rate of early diagnosis of cancer.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bladder Cancer | Malignant Bladder Neoplasm | CURATED_EXACT | 0.92 |
| Urothelial Carcinoma | Urothelial Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| RT-qPCR | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Case group （bladder cancer）
- description
- Urine exosomes were enriched for RT-qPCR within 4 hours after samples were collected.
- interventionNames
- Diagnostic Test: RT-qPCR
- label
- Control group （benigh）
- description
- Urine exosomes were enriched for RT-qPCR within 4 hours after samples were collected.
- interventionNames
- Diagnostic Test: RT-qPCR
- label
- Healthy people group
- description
- Urine exosomes were enriched for RT-qPCR within 4 hours after samples were collected.
- interventionNames
- Diagnostic Test: RT-qPCR
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Age ≥ 18 years with defined gender; 2. Preoperative patients are preliminarily evaluated as bladder tumors by cystoscopy, FISH, cytology, or imaging. Exclusion Criteria: 1. Aged \<18 years; 2. Post-operative or after anti-tumor treatment such as chemotherapy or immunotherapy 3. History of other malignant tumors 4. Specimens with hemolytic conditions; 5. Patients with incomplete, undocumented, and uncooperative data.
References
Publications (0)
Data not yet available