Clinical trial · Observational
Machine Learning Predicts Survival and Mutations in Ovarian Metastases of Colorectal Cancer
Machine Learning-based Model for Prediction of Survival and Mutations in Ovarian Metastases of Colorectal Cancer
NCT06192030CI-TRIAL-00072758unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study aimed to develop and validate models to predict survival outcome and key mutations in patients with ovarian metastases of colorectal cancer, as well as to compare the differential gene expression between long-survival group and short-survival group.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Ovarian Metastases of Colorectal Cancer | Krukenberg Tumor | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Prediction model | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Retrospective cohort
- description
- The cohort was retrospectively enrolled in The Sixth Affiliated Hospital, Sun Yat-sen University from August 2010 to August 2022. It is a training cohort.
- interventionNames
- Other: Prediction model
- label
- Prospective cohort
- description
- The same inclusion/exclusion criteria were applied for the same center prospectively. It is a validation cohort.
- interventionNames
- Other: Prediction model
Primary outcomes (3)
- measure
- Overall survival
- timeFrame
- At least 3-year follow up
- description
- Overall survival was defined as the time from surgery to death, or to the last follow-up.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: * Histologically confirmed colorectal cancer * Unilateral or bilateral ovarian masses confirmed by peroperative imaging examination * Patient requiring resection of their ovarian and/or peritoneal carcinomatosis * 18 ≤ Age ≤ 85 * World Health Organization performance status ≤ 1 * Life expectancy \> 12 weeks * Adequate haematological, liver and renal function * Patient information and signature of the informed consent form before the start of any treatment procedures Exclusion Criteria: * Ovarian metastases of origin other than colorectal * Primary ovarian tumor * Clinical data missing
References
Publications (0)
Data not yet available
No reference posted for this study.