Clinical trial · Interventional
Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors
A Pilot Randomized Trial of a Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to conduct a 6-month pilot randomized trial to determine the feasibility and acceptability of theory-based mobile weight loss interventions for survivors of adolescent and young adult cancer (AYAs). The interventions use a mobile smartphone application, previously developed for individuals at risk for type 2 diabetes and adapted for AYAs, that integrates weight and physical activity from digital devices with simplified dietary monitoring in a behavioral weight loss program.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Cancer Survivorship | — | UNRESOLVED | — |
| Mental Health | — | UNRESOLVED | — |
| Obesity | — | UNRESOLVED | — |
| Physical Activity | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| AYA Connect intervention | Behavioral | — | UNRESOLVED |
| Positive Psychology Plus (PP+) intervention | Behavioral | — | UNRESOLVED |
| Positive Psychology (PP) intervention | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- AYA Connect
- description
- Adolescent and young adult cancer survivors receive AYA Connect intervention.
- interventionNames
- Behavioral: AYA Connect intervention
- type
- EXPERIMENTAL
- label
- AYA Connect-PP
- description
- Adolescent and young adult cancer survivors receive AYA Connect-PP intervention.
- interventionNames
- Behavioral: AYA Connect intervention
- Behavioral: Positive Psychology (PP) intervention
- type
- EXPERIMENTAL
- label
- AYA Connect-PP+
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 39 Years
Show eligibility criteria text
In order to participate in this study a subject must meet all of the eligibility criteria outlined below. Inclusion Criteria: * Currently age 18-39 * Diagnosed with first invasive cancer between the ages of 15-39 years old * Within 10 years of diagnosis with no evidence of progressive disease or second primary cancers * Completed active cancer-directed therapy (cytotoxic chemotherapy, radiation therapy, and/or definitive surgical intervention) at least six months prior to enrollment, except maybe receiving "maintenance" therapy to prevent recurrences * Body Mass Index (BMI) of 25-50 kg/m2 Exclusion Criteria: * Type 1 diabetes or currently receiving medical treatment for Type 2 diabetes * Report a history of heart attack or stroke within the previous 6 months * Health problems that preclude the ability to walk for physical activity * Lost 5% or more of body weight (and kept it off) in the last 3 months * Past diagnosis of or receiving treatment for a clinically diagnosed eating disorder (anorexia nervosa or bulimia nervosa) or any compensatory behaviors within the previous 3 months * Currently pregnant, pregnant within the past 6 months, or planning to become pregnant within the next 6 months * Untreated thyroid disease or any changes (type or dose) in thyroid medication in the last 6 months * Hospitalization for depression or other psychiatric disorder within the past 12 months * History of psychotic disorder or bipolar disorder * Currently participating in a weight loss, nutrition, or physical activity study or program or other study that would interfere with this study * Currently using prescription medications with known effects on appetite or weight. * Previous surgical procedure for weight loss or planned weight loss surgery in the next 6 months * Inability to speak and read English * Do not have an iPhone with active data and text messaging plan * No Internet access * Not willing to be randomized to either intervention arm
References
Publications (0)
Data not yet available