Clinical trial · Observational
3D Ultrasound to Assess in Recurrent Miscarriage
Association of Acquired Uterine Abnormalities With Recurrent Miscarriage
NCT06164015CI-TRIAL-000721113D-ARMunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This observational study aims to compare the prevalence of acquired abnormalities of the uterus (fibroids, polyps, intrauterine adhesions, adenomyosis) in women who have recurrent miscarriages with the fertile population.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Recurrent Miscarriage | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 3D Ultrasound scan with power Doppler angiography | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Recurrent Miscarriage group (study group)
- description
- Group of women who have experienced 2 or more pregnancy loss of less than 24 weeks gestation.
- interventionNames
- Diagnostic Test: 3D Ultrasound scan with power Doppler angiography
- label
- Fertile population group (control group)
- description
- Group of women with proven fertility with at least one child born at full term
- interventionNames
- Diagnostic Test: 3D Ultrasound scan with power Doppler angiography
Primary outcomes (1)
- measure
- Prevalence of Acquired Uterine Anomalies
- timeFrame
- 24 months
- description
- Primary outcome will be to compare the prevalence of acquired uterine anomalies (estimated as the proportion of anomalies diagnosed on 3D pelvic ultrasound) between study group and control group
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 40 Years
Show eligibility criteria text
Inclusion Criteria: 1. Women between the age group of 18-40 years 2. Women who have had 2 or more pregnancy losses before 24 weeks of gestation - Study group. 3. Women who can provide documented informed consent 4. Women with proven fertility with at least one child - Control group Exclusion Criteria: 1\. Women with previous history of miscarriage/ extreme preterm delivery (before 28 weeks of gestation) will be excluded from the Control group.
References
Publications (3)
- RESULTChan YY, Jayaprakasan K, Tan A, Thornton JG, Coomarasamy A, Raine-Fenning NJ. Reproductive outcomes in women with congenital uterine anomalies: a systematic review. Ultrasound Obstet Gynecol. 2011 Oct;38(4):371-82. doi: 10.1002/uog.10056. PMID 21830244
- RESULTCarbonnel M, Pirtea P, de Ziegler D, Ayoubi JM. Uterine factors in recurrent pregnancy losses. Fertil Steril. 2021 Mar;115(3):538-545. doi: 10.1016/j.fertnstert.2020.12.003. PMID 33712099
- RESULTDobson SJA, Jayaprakasan KM. Aetiology of recurrent miscarriage and the role of adjuvant treatment in its management: a retrospective cohort review. J Obstet Gynaecol. 2018 Oct;38(7):967-974. doi: 10.1080/01443615.2018.1424811. Epub 2018 Mar 20. PMID 29557233