Clinical trial · Interventional
Efficacy of Inhaled Aromatherapy on Nausea and Vomiting in Hematological Malignancies
Efficacy of Ginger and Lemon Essential Oil Inhalation on Chemotherapy-induced Nausea and Vomiting in Patients with Haematological Malignancies: a Multicenter, Double-blind, Randomised Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This project will optimise the management of chemotherapy-induced nausea and vomiting, with improvements in nausea and vomiting scores, quality of life and appetite expected in participants benefiting from the intervention. In all cases, the use of complementary methods is recommended and improves the management of people with cancer because they offer a person-centred approach.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hematological Malignancies | Hematopoietic and Lymphoid Cell Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| "Blend of ginger and lemon essential oils", "Neutral oil" | Combination Product | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Blend of ginger and lemon essential oils
- description
- The experimental group will benefit from conventional management of NVCI (antiemetic prophylaxis in accordance with ESMO international recommendations) plus an aromastick of ginger and lemon essential oils renewed with each course of chemotherapy. Patients were included for 3 cycles of chemotherapy (C1, C2, C3).
- interventionNames
- Combination Product: "Blend of ginger and lemon essential oils", "Neutral oil"
- type
- PLACEBO_COMPARATOR
- label
- Neutral oil
- description
- The control group will receive conventional management (antiemetic prophylaxis according to international recommendations, ESMO) of NVCI plus a placebo of aromastick containing a neutral, odourless oil, renewed with each course of chemotherapy.
- interventionNames
- Combination Product: "Blend of ginger and lemon essential oils", "Neutral oil"
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients aged over 18 years, * Chemo-naive patients at inclusion, * Patients with haematological malignancies treated treated with chemotherapy, * Patients physically and mentally able to use the aromastick, * Patients who speak, read and write French, * Patients who have given signed consent, * Patients with social security cover. Exclusion Criteria: * Asthmatic patients. * Patients with anosmia. * Patients allergic to EO, lemon or ginger. * Patients who have already received aromatherapy to treat chemotherapy-induced nausea and vomiting, * Patients practising herbal medicine or acupuncture, * Pregnant and breast-feeding women, * Patients under guardianship, tutorship or curatorship, * Patients taking part in interventional studies involving antiemetic drugs or nutritional products, * Patients who have already had cancer.
References
Publications (0)
Data not yet available