Clinical trial · Interventional
Coughing at Time of Cervical Biopsy
Pain Reduction by Forced Coughing During Colposcopy Guided Cervical Biopsies: a Randomized Controlled Pilot Study
NCT06149598CI-TRIAL-00086730completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To investigate the effect of coughing as an intervention to reduce pain in colposcopy guided biopsy.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cervical Biopsy | — | UNRESOLVED | — |
| Cervical Cancer | Malignant Cervical Neoplasm | CURATED_EXACT | 0.92 |
| Cervical Dysplasia | Cervical Intraepithelial Neoplasia | ALIAS | 0.90 |
| Colposcopy | — | UNRESOLVED | — |
| Pain Sensation | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Coughing at the time of biopsy | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Coughing at the time of first biopsy
- description
- Patients are asked to cough during the first biopsy. They should not cough during the second biopsy, and no additional interventions will be performed during the second biopsy.
- interventionNames
- Behavioral: Coughing at the time of biopsy
- type
- ACTIVE_COMPARATOR
- label
- Coughing at the time of second biopsy
- description
- Patients are asked to cough during the second biopsy. They should not cough during the first biopsy, and no additional interventions will be performed during the first biopsy.
- interventionNames
- Behavioral: Coughing at the time of biopsy
Primary outcomes (1)
- measure
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Completed 18 years of age * written informed consent * first colposcopy * Clinically indicated colposcopy in case of an abnormal PAP smear or screening result and/or clinical abnormalities on the cervix uteri * Necessity to take exactly two biopsies Exclusion Criteria: * Performing only one biopsy or more than two biopsies * Performing an endocervical curettage (biopsy on the endocervix) * Vaginal bleeding at the time of examination * inadequate colposcopy * Cervix uteri cannot be fully visualized * Pregnancy * Patients with insufficient German language skills * known anxiety disorders or depressive disorders * Treatments already carried out on the cervix uteri * Patients with a chronic or acute illness that influences the perception of pain or lead to permanent pain due to the disease itself * psychosomatic illnesses * Chronic use of pain medications or psychotropic medications or other medications that may have an influence on the sensation of pain
References
Publications (0)
Data not yet available
No reference posted for this study.