Clinical trial · Interventional
Web Intervention for Parents of Youth With Genetic Syndromes (WINGS)
Promoting Prosocial Behavior in Syndromic Intellectual and Developmental Disabilities
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 19, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260919-000001
Summary
Brief summary (as posted)
The purpose of this study is to evaluate the effectiveness of an adapted, telehealth functional behavioral therapy (FBTsIDD) specifically focused on promoting appropriate communication and behavioral strategies in individuals with syndromic intellectual and developmental disorders. Participants will be asked to complete virtual study assessments at intake and then on a monthly basis for the duration of 3-6 months. In addition, participants will attend weekly or biweekly virtual intervention visits with a study therapist.
Conditions
Conditions (8)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Angelman Syndrome | — | UNRESOLVED | — |
| Chromosome 15Q, Partial Deletion | — | UNRESOLVED | — |
| Creatine Deficiency, X-linked | — | UNRESOLVED | — |
| Fragile X Syndrome | — | UNRESOLVED | — |
| Hamartoma Syndrome, Multiple | — | UNRESOLVED | — |
| Rett Syndrome | — | UNRESOLVED | — |
| Telomeric 22Q13 Monosomy Syndrome | — | UNRESOLVED | — |
| Tuberous Sclerosis | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Functional Behavioral Training (FBT) | Behavioral | — | UNRESOLVED |
| Positive Parenting Strategies-Treatment as Usual | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Functional Behavioral Training
- interventionNames
- Behavioral: Functional Behavioral Training (FBT)
- type
- ACTIVE_COMPARATOR
- label
- Positive Parenting Strategies-Treatment As Usual
- interventionNames
- Other: Positive Parenting Strategies-Treatment as Usual
Primary outcomes (1)
- measure
- Clinical Global Impression
- timeFrame
- TO (Baseline), T2 (Month 2), T4 (Month 4), T6 (Month 6)
- description
- Overall functioning will be measured using the Clinical Global Impression for Severity (CGI-S) and Improvement (CGl-I). GCI-S will be recorded at Baseline with CGI-S and CGI-I collected at all determined visits. The CGI provides a rating of the child's global functioning, taking into account all available information (e.g., child's symptoms, behavior, functioning). The CGI-S and CGl-I will be completed by a blinded independent evaluator.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 2 Years
- Maximum age
- 12 Years
Show eligibility criteria text
Inclusion Criteria: * Age(s) 2-12 years old at time of enrollment * Existing genetic syndrome based on clinical or genetic diagnosis and confirmed by medical records * Documented diagnosis of global developmental delay (GDD) or intellectual disability (ID) * estimated ID in all ranges * Disruptive behavior challenges determined to be clinically appropriate for remote, parent-implemented coaching based on clinician determination of acuity of problem behaviors * Caregiver who is able to consent in English. * Parent/caregiver available for weekly intervention sessions * Stable psychosocial and psychiatric treatments 3 months prior to baseline visit. Exclusion Criteria: * High levels of aggression that mitigate remote or outpatient treatment as defined by clinician judgement and/or ABC Irritability scores above 20 (i.e., higher level of care needed than provided by study procedures) * Medical or psychiatric instability that may limit study participation * Meaningful change in medication or psychosocial interventions 3 months prior to baseline visit * Limitations in technology access that may hinder participation in remote trial (e.g., declining support provided by study participation)
References
Publications (0)
Data not yet available