Clinical trial · Interventional
Effect of Time-restricted Eating on Cognitive Function and Other Biopsychosocial Factors in Menopausal Women Undertaking a 12-week Exercise Programme
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this quasi-experimental study is to test effect of time-restricted eating on cognitive function and other biopsychosocial factors in menopausal women undertaking a 12-week exercise programme. The main questions to answer are: 1. What is effect of time-restricted eating on cognitive function in menopausal women undertaking a 12-week exercise programme? 2. What is effect of time-restricted eating on menopausal symptoms in menopausal women undertaking a 12-weeks exercise programme? 3. What is effect of time-restricted eating on metabolic health parameters in menopausal women undertaking a 12-weeks exercise programme? Participants of both groups will have moderate intensity circuit mixed endurance and resistance exercise programme two times per week for 55 minutes for 12 weeks. Participants of one of two groups will not only exercise but also have a time-restricted eating following 16:8 protocol for 12 weeks. Participants will have pre-tests and post-tests: * blood samples collection (to measure level of brain-derived neurotrophic factor, glial cell derived neurotrophic factor, insulin, glucose, lipid profile), * body composition analysis, * Stroop test and N-back test, * electroencephalography using Emotiv Epic X devices, * One-repetition maximum test, Ruffier test, * Questionnaire assessment (using Menopause Rating Scale and The Menopause-Specific Quality of Life Questionnaire). Researchers will compare two groups - exercise group and combination group which will do both time-restricted eating and exercise to see if there is a modulating effect of time-restricted eating in participants undertaking exercise.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cognitive Deficits, Mild | — | UNRESOLVED | — |
| Menopause | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Exercise and Time-Restricted Eating | Behavioral | — | UNRESOLVED |
| Exercise only | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Exercise and Time-Restricted Eating
- interventionNames
- Behavioral: Exercise and Time-Restricted Eating
- type
- ACTIVE_COMPARATOR
- label
- Exercise only
- interventionNames
- Behavioral: Exercise only
Primary outcomes (14)
- measure
- Brain-derived neurotrophic factor
- timeFrame
- Before and after 12-week intervention
- description
- Level of brain-derived neurotrophic factor in ng/ml
- measure
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 41 Years
- Maximum age
- 61 Years
Show eligibility criteria text
Inclusion Criteria: * perimenopause, menopause or post-menopause * lightly physically active or physically inactive Exclusion Criteria: * using hormone replacement therapy or hormonal contraception * having significant contraindications to physical exercise or time-restricted eating
References
Publications (2)
- DERIVEDJozwiak B, Kleka P, Laudanska-Krzeminska I. Effect of exercise alone and in combination with time-restricted eating on cognitive health in menopausal women. Front Public Health. 2025 Aug 13;13:1640512. doi: 10.3389/fpubh.2025.1640512. eCollection 2025. PMID 40880914
- DERIVEDJozwiak B, Domin R, Krzywicka M, Laudanska-Krzeminska I. Effect of exercise alone and in combination with time-restricted eating on cardiometabolic health in menopausal women. J Transl Med. 2024 Oct 21;22(1):957. doi: 10.1186/s12967-024-05738-y. PMID 39434160