Clinical trial · Interventional
Risk-Adapted Treatment Strategies for Odontogenic Keratocysts: A Long-Term Randomized Clinical Trial Quantifying Recurrence Reduction
Analysis of Odontogenic Keratocyst Treated With Various Modalities Over a 10-year
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Background The odontogenic keratocysts (OKCs) have been one of the maxillofacial region's most contentious pathological phenomena. Decompression/marsupialization (D/M), enucleation (E), enucleation + chemical cauterization with Carnoy's solution (E+CS), enucleation + peripheral ostectomy (E + PO), as opposed to enucleation + chemical cauterization with Carnoy's solution + peripheral ostectomy (E + CS + PO), were used during surgery to ensure that no epithelial remnants were left behind. Rationale Through the management of OKC a recurrence could occur, the effectiveness of Decompression/marsupialization (D/M), Enucleation (E), Enucleation+Carnoy's solution chemical cauterization (E+CS), Enucleation+peripheral ostectomy (E+PO), Enucleation+Carnoy's solution chemical cauterization + peripheral ostectomy (E+CS + PO), will be analyzed
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Odontogenic Cysts | — | UNRESOLVED | — |
Interventions
Interventions (5)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Decompression/ marsupialization (D/M) | Procedure | — | UNRESOLVED |
| Enucleation+Carnoy's solution (E+CS) | Procedure | — | UNRESOLVED |
| Enucleation (E) | Procedure | — | UNRESOLVED |
| Enucleation+ Peripheral Ostectomy+Carnoy's solution chemical cauterization (E+CS + PO) | Procedure | — | UNRESOLVED |
| Enucleation+ Peripheral Ostectomy (E+ PO) | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (5)
- type
- EXPERIMENTAL
- label
- Enucleation + Peripheral ostectomy + Carnoy's solution chemical cauterization (E+ PO+ CS)
- description
- The odontogenic keratocysts will be treated using enucleation, followed by peripheral ostectomy and then Carnoy's solution
- interventionNames
- Procedure: Enucleation+ Peripheral Ostectomy+Carnoy's solution chemical cauterization (E+CS + PO)
- type
- EXPERIMENTAL
- label
- Decompression/marsupialization (D/M)
- description
- The odontogenic keratocysts will be managed by either Decompression or marsupialization
- interventionNames
- Procedure: Decompression/ marsupialization (D/M)
- type
- EXPERIMENTAL
- label
- Enucleation (E)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 10 Years
Show eligibility criteria text
Inclusion Criteria: * All odontogenic keratocysts that are treated by the following surgical treatment modalities: 1. Enucleation followed by peripheral ostectomy and Carnoy's solution 2. Decompression/ marsupialization 3. Enucleation 4. Enucleation and Carnoy's solution 5. Enucleation and Peripheral Ostectomy * Follow-up period 10 years Exclusion Criteria: * Cases treated with resection * Cases showed neoplastic transformation in their pathology * Cyst Like lesions
References
Publications (0)
Data not yet available