Clinical trial · Interventional
Application of Perioperative Remote Ischemic Conditioning in Patients Undergoing Hepatectomy
NCT06130436CI-TRIAL-00079890completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Our primary aim is to investigate whether perioperative remote ischemic conditioning (PRIC) as an adjunctive treatment can improve postoperative recovery in patients undergoing hepatectomy as an adjunct to standard treatment.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hepatectomy | — | UNRESOLVED | — |
| Hepatic Hemangioma | Liver Hemangioma | ALIAS | 0.90 |
| Hepatolithiasis | — | UNRESOLVED | — |
| Liver Cancer | Malignant Liver Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Remote Ischemic Conditioning Once Daily | Device | — | UNRESOLVED |
| Remote Ischemic Conditioning Twice Daily | Device | — | UNRESOLVED |
| Sham-Remote Ischemic Conditioning | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- SHAM_COMPARATOR
- label
- Sham-Remote Ischemic Conditioning
- description
- Sham remote ischemic conditioning (Sham-RIC) is applied in the perioperative using an automated Sham-RIC device.
- interventionNames
- Device: Sham-Remote Ischemic Conditioning
- type
- ACTIVE_COMPARATOR
- label
- Remote Ischemic Conditioning Once Daily
- description
- Remote ischemic conditioning (RIC) is applied in the perioperative using an automated RIC device once daily.
- interventionNames
- Device: Remote Ischemic Conditioning Once Daily
- type
- ACTIVE_COMPARATOR
- label
- Remote Ischemic Conditioning Twice Daily
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 25 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Patients undergoing hepatectomy under general anesthesia * American Society of Anesthesiology (ASA) grade of II \~ III * Male and female patients, age 25 to 75 years * New York Heart Association (NYHA) grade of I \~ III Exclusion Criteria: * Patients with limb deformity or peripheral vascular disease affecting upper limb function * Patients with a medical history of nervous system, immune system and mental illness * Patients who have received hepatectomy in the past, have important organ diseases or have undergone surgical treatment recently * Patients who have recently used anti-inflammatory analgesics, anticoagulants, hormone drugs, immunosuppressants, and ATP-sensitive K-channel blockers (KATP) * Preoperative severe renal insufficiency (serum creatinine \> 442 umol/L, with or without serum potassium \> 6.5 mmol/L, or the clinician-recognized need for renal replacement therapy), liver insufficiency (Child-Pugh grade C) * Patients and/or their family members refuse to participate in the program
References
Publications (1)
- DERIVEDTian C, Tian H, Li W, Chen J, Guo Q, Duan G, Huang H. Effects of Remote Ischemic Conditioning on Postoperative Recovery After Hepatectomy: A Randomised Controlled Trial. Liver Int. 2025 Mar;45(3):e70041. doi: 10.1111/liv.70041. PMID 39982031