Clinical trial · Observational
A Study to Identify Barriers to Cellular Therapies for People With Plasma Cell Disorders
Prospective Multi-Center Study to Identify Barriers to Cellular Therapies in Patients With Plasma Cell Disorders PROACT PCD
NCT06126341CI-TRIAL-00103685active not recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is an observational study that will include both participants with relapsed/refractory Multiple Myeloma and their doctors. The purpose of this study is to gather information about the use of hematopoietic cell transplantation/HCT and B-cell maturation antigen /BCMS targeted chimeric antigen receptor/CAR autologous T-cell therapy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Multiple Myeloma | Multiple Myeloma | CURATED_EXACT | 0.92 |
Interventions
Interventions (6)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Distress Thermometer | Behavioral | — | UNRESOLVED |
| Duke-UNC Functional Social Support Questionnaire | Behavioral | — | UNRESOLVED |
| FACT-BMT | Behavioral | — | UNRESOLVED |
| Hospital Anxiety and Depression Scale | Behavioral | — | UNRESOLVED |
| Lecture on the role of cellular therapies in relapse/refractory multiple myeloma/RRMM | Other | — | UNRESOLVED |
| Psychosocial Assessments of Candidates for Transplantation | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (5)
- label
- Participant Cohort 1
- description
- Relapse/refractory multiple myeloma/RRMM patients less than 70 years of age.
- interventionNames
- Behavioral: Hospital Anxiety and Depression Scale
- Behavioral: Duke-UNC Functional Social Support Questionnaire
- Behavioral: Distress Thermometer
- Behavioral: FACT-BMT
- Behavioral: Psychosocial Assessments of Candidates for Transplantation
- label
- Participant Cohort 2
- description
- Relapse/refractory multiple myeloma/RRMM patients 70 years of age or greater
- interventionNames
- Behavioral: Hospital Anxiety and Depression Scale
- Behavioral: Duke-UNC Functional Social Support Questionnaire
- Behavioral: Distress Thermometer
- Behavioral: FACT-BMT
- Behavioral: Psychosocial Assessments of Candidates for Transplantation
- label
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: Patient * Diagnosis of Multiple Myeloma after January 1, 2017. * Karnofsky Performance Status \> 70% * ≥ 2 lines of prior therapy * Anticipated to start new a line of therapy for RRMM within the next 12 months * Age 18-80 years of age. * English or Spanish speaking. * Willing to provide informed consent * Willing to perform study procedures. Physician Investigator * Be a Co-Investigator * Agree to comply with study procedures Exclusion Criteria: Patient * Active CNS disease * Patients who already have a definitive plan are to be excluded
References
Publications (0)
Data not yet available
No reference posted for this study.