Clinical trial · Interventional
CompariSon Between the EuroPeAn and Japanese pathologiCal InvEstigation for Colon Cancer (SPACE)
Comparison Between the European and Japanese Pathological Investigation for Colon Cancer (SPACE)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In general, the European pathological examination method primarily relies on pathologists and does not require the involvement of surgeons. The Japanese pathological evaluation approach, on the other hand, involves the intervention of surgeons, particularly in the extraction of lymph nodes from fresh specimens and the assessment of specimen quality. Given that the Japanese pathological assessment method lacks systematic evaluation and there is currently no literature clearly demonstrating its diagnostic accuracy, the main objective of this study is to verify whether the diagnostic accuracy of the Japanese pathological investigation method is inferior to that of the European pathological evaluation method.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colonic Neoplasms | Colon Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| European pathological investigation | Procedure | — | UNRESOLVED |
| Japanese pathological investigation | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Japanese pathological investigation method group
- description
- The surgeon will be involved into the Japanese pathological investigation method. The surgeon will perform the intraoperative markings and the postoperative lymph node harvest, after which the specimen will be assessed by the pathologist.
- interventionNames
- Procedure: Japanese pathological investigation
- type
- ACTIVE_COMPARATOR
- label
- European pathological investigation method group
- description
- After receiving the resected specimen, the entire process will be independently managed by the pathologist.
- interventionNames
- Procedure: European pathological investigation
Primary outcomes (1)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Patients diagnosed with colon cancer who underwent colectomy; * Patients with pathological confirmed adenocarcinoma; * Patients agreed to participate in the study. Exclusion Criteria: * Patients suffered from rectal cancer; * Patients diagnosed with colon cancer but did not undergo colectomy; * Patients refused participation.
References
Publications (0)
Data not yet available