Clinical trial · Interventional
Enchasing Polyp Detection: The Effect of Adding Polyp Detection Attachment Device to Computer Aid Detection System.
Enhancing Polyp Detection: A Randomized Controlled Trial Comparing Combined Computer-Aid Detection and Polyp-Detecting Colonoscope Attachment to Computer-Aid Detection Alone in Patients Undergoing Colonoscopy.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Despite the widespread use of colonoscopy, the ongoing challenge of potentially missing polyps remains. Previous studies have independently shown that both Endocuff, a colonoscope attachment device for polyp detection, and Computer-Aided Detection (CADe) systems have individually demonstrated enhanced lesion detection and safety. This study seeks to evaluate the efficacy of combining the Endocuff CADe versus using CADe alone in colonoscopy procedures for colorectal cancer screening and surveillance. This research project aims to ascertain whether the synergistic application of these technologies yields superior outcomes.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Cancer Screening | — | UNRESOLVED | — |
| Colon Cancer Surveillance | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Endocuff and GI Genius | Device | — | UNRESOLVED |
| GI Genius | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Endocuff + GI Genius
- description
- Endocuff is a polyp-detecting colonoscope attachment device. GI Genius is and Computer-Aid Detection (CADe) system to detect polyps
- interventionNames
- Device: Endocuff and GI Genius
- type
- ACTIVE_COMPARATOR
- label
- GI Genius
- description
- GI Genius is and Computer-Aid Detection (CADe) system to detect polyps
- interventionNames
- Device: GI Genius
Primary outcomes (1)
- measure
- Adenoma detection rate
- timeFrame
- 18 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age \> 18 * Patients scheduled for an outpatient screening or surveillance colonoscopy. Exclusion Criteria: * Patients who require diagnostic colonoscopy (e.g.; anemia or GI bleeding). * Patients requiring deep ileal intubation. * Patients with inflammatory bowel disease. * Patients with radiotherapy-induced colitis or other severe colitis. * Patients with colonic strictures. * Patients with acute diverticulitis. * Patients with large bowel obstruction. * Patients scheduled for therapeutic colonoscopy (e.g., planned endoscopic mucosal resection for known polyps). * Patients scheduled for assessment of a known colonic lesion. * Patients with a known history of hereditary polyposis syndrome or untreated colon cancer. * Patients with a history of colon resection. * Patients on continuous anti-thrombotic therapy * Pregnancy. * Patients who are ineligible for colonoscopy due to medical or psychiatric conditions. * Patients who are vulnerable or unable to consent
References
Publications (0)
Data not yet available