Surgical Treatment and Molecular Marker Exploration of Locally Recurrent Colorectal Cancer

This study intends to explore the clinicopathological characteristics and survival prognosis of locally recurrent colorectal cancer patients with different treatment modes by retrospectively analyzing the medical records of locally recurrent colorectal cancer patients who received hospitalization in our center. Transcriptome sequencing and public databases were used to screen for molecular markers related to locally recurrent colorectal cancer and to explore molecular markers' regulatory role in the progression of locally recurrent colorectal cancer.

Sex

All

Minimum age

18 Years

Maximum age

85 Years

Inclusion Criteria:

1. Patients with LRCRC who received hospitalization in our center and patients with stage II-III colorectal cancer whose primary surgery was radical surgery
2. The pathological type of primary tumor is adenocarcinoma
3. Postoperative local recurrence of colorectal cancer diagnosed by imaging or pathological examination
4. Have complete medical records and continuous follow-up records

Exclusion Criteria:

1. Familial hereditary colorectal malignant tumors
2. Past history of other malignant tumors
3. Recurrence and diffuse peritoneal recurrence occurring within 1 month after surgery

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