Clinical trial · Observational
Molecular Characterization of Penile Cancers in Developing Countries
NCT06068998CI-TRIAL-00070223completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study explores penile squamous cell carcinoma (PSCC) in Brazil, a rare cancer associated with factors like poor hygiene and HPV infection, using next-generation sequencing to investigate its genomic profiles in 24 deceased patients with advanced PSCC.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Penile Squamous Cell Carcinoma | Penile Squamous Cell Carcinoma | CURATED_BROADER | 0.80 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Biomarker Profiling of Penile Carcinoma by NGS
- timeFrame
- Through study completion, an average of 2 years
- description
- The study employs state-of-the-art molecular analysis methods, including next-generation sequencing (NGS) using a targeted panel (FoundationONE CDx) that assesses 324 genes.
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Men ≥ 18 years of age; * Diagnosis of locally advanced or metastatic squamous-cell penile carcinoma; * Have received at least one treatment for advanced disease (surgery, radiotherapy and/or chemotherapy); * Available representative tumor block of formalin-fixed and paraffin-embedded (FFPE) archive, from primary or metastasis; * Patients must be already deceased at time of data collection. Exclusion Criteria: * Patients without medical record available (lost, empty or irretrievable clinical information).
References
Publications (0)
Data not yet available
No reference posted for this study.