Clinical trial · Interventional
Robotic Right Hemicolectomy Versus Laparoscopic Right Hemicolectomy
Robotic Right Hemicolectomy With Intracorporeal Anastomosis Versus Laparoscopic Right Hemicolectomy With Extracorporeal Anastomosis (PRORHEM): a Randomized Controlled Trial
NCT06067620CI-TRIAL-00077050PRORHEMnot yet recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Robotic right hemicolectomy with intra-corporeal anastomosis may have better short-term recovery outcomes and decreased incidence of incisional hernia when compared to the laparoscopic actual standard of care, for similar safety outcomes.
Conditions
Conditions (7)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Adenocarcinoma | Colorectal Adenocarcinoma | ONTOLOGY_EXACT | 0.98 |
| Colorectal Adenoma | Colorectal Adenoma | ONTOLOGY_EXACT | 0.98 |
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Colorectal Neoplasms | Colorectal Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Colorectal Neoplasms, Benign | Benign Colorectal Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Colorectal Neoplasms Malignant | Colon Neoplasm | PROBABILISTIC | 0.70 |
| Colorectal Polyp | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Laparoscopic right hemicolectomy | Procedure | — | UNRESOLVED |
| Robotic right hemicolectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Robotic right hemicolectomy
- description
- Robotic right hemicolectomy with intracorporeal anastomosis and extraction through a C-section (fully minimally invasive right hemicolectomy)
- interventionNames
- Procedure: Robotic right hemicolectomy
- type
- ACTIVE_COMPARATOR
- label
- Laparoscopic right hemicolectomy
- description
- Laparoscopic right hemicolectomy with extracorporeal anastomosis and extraction through midline (standard of care)
- interventionNames
- Procedure: Laparoscopic right hemicolectomy
Primary outcomes (1)
- measure
- Time to first passage of faeces
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Adult patients requiring elective minimally invasive RHC for cT1-T3 Nx M0 cancer of the right colon (including cancer of the appendix, caecum, ascending colon and hepatic flexure). Exclusion Criteria: * Not scheduled for minimally invasive RHC (refuses surgery and/or planned open approach) * Emergency surgery * Hereditary colorectal cancer * Inflammatory bowel disease * Synchronous resection of (an)other organ(s) * Synchronous surgical procedure (including more extended resection of the lower gastrointestinal tract) * cT4 * cM+ * History of laparotomy * Pregnancy * No anastomosis planned * Unable to provide informed consent * No informed consent
References
Publications (1)
- DERIVEDMeyer J, Liot E, Meurette G, Toso C, Ris F. Robotic right hemicolectomy with intracorporeal anastomosis versus laparoscopic right hemicolectomy with extracorporeal anastomosis (PRORHEM): protocol for a randomized controlled trial. BMC Surg. 2026 Jul 8. doi: 10.1186/s12893-026-03990-1. Online ahead of print. PMID 42420958