Clinical trial · Observational
Robot-assisted vs Laparoscopic vs Open Radical Cholecystectomy for Gallbladder Cancer
Robot-assisted vs Laparoscopic vs Open Radical Cholecystectomy for Gallbladder Cancer: a Multicenter Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The gallbladder is the most common primary cancer site among the biliary tracts and its incidence is increasing. Its prognosis is still poor with a 5-year survival of almost 20%. Cholecystectomy is curative in patients with Tis and T1a. For patients with resectable T1b and above disease, radical cholecystectomy is advocated consisting of en bloc resection of the gallbladder, wedge resection of the liver or segment 4b, extrahepatic bile duct, and the regional lymph nodes. The aim of this study is to compare patients who have undergone Robotic, Laparoscopic and Open liver resection with lymphadenectomy for \>T1b gallbladder cancers in a case-matched analysis using propensity scores. The primary endpoints are intra- and postoperative outcomes, and the secondary endpoints long-term oncologic outcomes and feasibility and adequacy of minimally invasive versus traditional open approach.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gallbladder Cancer | Malignant Gallbladder Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Minimally invasive surgery | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Open approach
- description
- Gallbladder cancer with hepatectomy and lymphadenectomy which underwent surgery by classical open approach
- label
- Robotic approach
- description
- Gallbladder cancer with hepatectomy and lymphadenectomy which underwent surgery by any type of robotic surgical device approach
- interventionNames
- Other: Minimally invasive surgery
- label
- Laparoscopic approach
- description
- Gallbladder cancer with hepatectomy and lymphadenectomy which underwent surgery by laparoscopic approach
- interventionNames
- Other: Minimally invasive surgery
Primary outcomes (7)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * \>T1b gallbladder cancers * Age at least 18 years; * Types of surgery include Robotic, Laparoscopic and Open approach * A statement by each centre will be required confirming the number of procedures - minimum 1 year of follow up Exclusion Criteria: \- not completed data
References
Publications (0)
Data not yet available