Association Between Body Composition and Digestive System Cancer Survival

Inclusion Criteria:

* Male or female patients aged between 18 and 85 years old.
* Patients with histologically confirmed digestive tract cancers, such as esophageal cancer, gastric cancer, small intestinal cancer, colorectal cancer, as well as pancreatic cancer, liver cancer, gallbladder cancer, etc.
* Patients admitted for anti-tumor-related drug treatment.
* Expected survival period of more than three months.
* ECOG PS score: \< 4.
* No severe psychological disorders, physical disabilities, dementia, Alzheimer's disease, pulmonary tuberculosis, HIV/AIDS, or other infectious diseases.
* Patients must have sufficient organ and bone marrow function, meeting the following criteria:

  1. Hematological criteria:

     Hemoglobin (Hb) ≥ 90 g/L (without blood transfusion in the past 28 days). Absolute neutrophil count (ANC) ≥ 1.5×109/L. Peripheral blood monocytes \> 1500mm3. Platelet count (PLT) ≥ 100×109/L.
  2. Biochemical criteria:

     Total bilirubin (TBIL) ≤ 1.5 × the upper limit of normal (ULN). ALT and AST ≤ 2.5×ULN; if there is liver metastasis, ALT and AST ≤ 5×ULN. Creatinine (Cr) ≤ 1.5×ULN or creatinine clearance rate (CCr) ≥ 60 ml/min (Cockcroft-Gault formula).
  3. Coagulation function is sufficient, defined as international normalized ratio (INR) or prothrombin time (PT) ≤ 1.5 × ULN.
* Women of childbearing potential must have a negative pregnancy test (serum or urine) within seven days before enrollment and must voluntarily use appropriate contraception methods during the observation period and within six months after the last dose.
* Signed informed consent.

Exclusion Criteria:

* Female patients who are pregnant or breastfeeding.
* Patients with accompanying diseases, as judged by the investigator, pose a serious risk to patient safety or may affect the patient's ability to complete the study.
* Patients with poor compliance who refuse to undergo body composition measurements.
* Patients who experience a severe adverse event judged by the investigator as no longer suitable for continued participation in the study or those who become unexpectedly pregnant.
* Patients who are unwilling to continue in the clinical trial and insist on withdrawal.
* The investigator deems it necessary to terminate the study.
* Patients who were mistakenly included but did not meet the criteria.