Clinical trial · Observational
Comparison of 3 in Vivo Microscopic Imaging Techniques for the Diagnosis of Pigmented Tumors
Comparison of 3 in Vivo Microscopic Imaging Techniques for the Diagnosis of Pigmented Tumors. Monocentric Retrospective Study of 170 Tumors
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Reflectance confocal microscopy (RCM) is the reference in vivo imaging technique for identifying malignant melanocytic tumors prior to surgical excision. However, it is not widely used due to its high cost and highly technical and time-consuming nature. In addition to Reflectance confocal microscopy (RCM), it currently use 2 less expensive dermatoscopes that also allow in vivo diagnosis: super-high magnification dermoscopy (D400) and Fluorescence-Advanced videodermatoscopy (FAV).
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Basal Cell Carcinoma | Basal Cell Carcinoma | ONTOLOGY_EXACT | 0.90 |
| Lentigo | — | UNRESOLVED | — |
| Lentigo Maligna | Lentigo Maligna | ONTOLOGY_EXACT | 0.98 |
| Melanoma | Melanoma | ONTOLOGY_EXACT | 0.98 |
| Nevus | Nevus | ONTOLOGY_EXACT | 0.98 |
| Seborrheic Keratosis | Seborrheic Keratosis | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Fluorescence-Advanced videodermatoscopy | Diagnostic Test | — | UNRESOLVED |
| Reflectance confocal microscopy | Diagnostic Test | — | UNRESOLVED |
| Super-high magnification dermoscopy | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Patients with a pigmented skin lesion
- description
- Patients with a pigmented skin lesion of more than 3mm diameter which have benefited systematically of all 3 imaging techniques at the same time, followed by either a surgical excision or annual imaging monitoring.
- interventionNames
- Diagnostic Test: Fluorescence-Advanced videodermatoscopy
- Diagnostic Test: Reflectance confocal microscopy
- Diagnostic Test: Super-high magnification dermoscopy
Primary outcomes (1)
- measure
- To compare the the relevance of each technique for the diagnostic of pigmented lesions.
- timeFrame
- Day 1
- description
- The nature of the tumor is diagnosed by the imaging technique.
Secondary outcomes (1)
- measure
- Comparison of performance of imaging techniques
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Patients with a pigmented skin lesion of more than 3mm diameter which have benefited systematically of all 3 imaging techniques at the same time, followed by either a surgical excision or annual imaging monitoring. Exclusion Criteria: * Bad quality images * Insufficient number of images * Uncertain diagnosis given by the pathologist * Refusal
References
Publications (0)
Data not yet available