Clinical trial · Interventional
The Occurrence of Emergence Agitation in Pediatric Strabismus Surgery
The Effect of Administration of Sugammadex on the Occurrence of Emergence Agitation in Pediatric Strabismus Surgery-prospective Randomized Controlled Trial
NCT06035757CI-TRIAL-00118046completedPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The present trial conducted to demonstrate the administration of sugammadex as reversal of neuromuscular blockade agent reduces the incidence of emergence agitation (EA) comparing to neostigmine
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Emergence Delirium | — | UNRESOLVED | — |
| Pediatric ALL | Childhood Acute Lymphoblastic Leukemia | ALIAS | 0.90 |
| Strabismus | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Bridion 200 MG in 2 ML Injection | Drug | — | UNRESOLVED |
| Pyridostigmine Bromide 5 MG/ML | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- group pyridostigmine
- description
- If TOF count is 1 or less, wait until it becomes 2 and then give the patient pyridostigmine dose of 350mcg/kg. If TOF count shows 4 with fade, 350mcg/kg of pyridostigmine is administered and without fade, 200mcg/kg is administered.
- interventionNames
- Drug: Pyridostigmine Bromide 5 MG/ML
- type
- ACTIVE_COMPARATOR
- label
- group sugammadex
- description
- If TOF count shows 0 and PTC (posttetanic count) is 1 or more, sugammadex administered dose of 4mg/kg. If TOF count shows 1 or more, 2mg/kg is administered.
- interventionNames
- Drug: Bridion 200 MG in 2 ML Injection
Primary outcomes (1)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 4 Years
- Maximum age
- 7 Years
Show eligibility criteria text
Inclusion Criteria: * Patients scheduled elective strabismus surgery aged 4-7 with American Society of Anesthesiologists (ASA) classification 1-3. Exclusion Criteria: * ASA classification 3 or more * impaired liver function * impaired kidney function * myasthenia gravis or other neuromuscular disorders * history of drug allergy * cardiovascular disease or arrhythmia
References
Publications (0)
Data not yet available
No reference posted for this study.