Clinical trial · Interventional
Applications of Fluorescence Imaging Guided Lymph Node Dissection and Fluorescence Angiography of Inferior Mesenteric Artery Assisted Left Colic Artery Preservation
Applications of Near-infrared Fluorescence Imaging Guided Lymph Node Dissection and Fluorescence Angiography of Inferior Mesenteric Artery Assisted Left Colic Artery Preservation: A Prospective Randomized Controlled Study
NCT06033794CI-TRIAL-00069564unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To investigate the accuracy of fluorescence angiography technique IMA classification and the impact of lymph node mapping technique on the dissection of No. 253 lymph nodes.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Fluorescence | — | UNRESOLVED | — |
| Indocyanine Green | — | UNRESOLVED | — |
| Rectal Cancer Surgery | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Fluorescence laparoscopic system | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Laparoscopic No. 253 lymph node dissection and preserving the LCA under fluorescence guidance.
- description
- Preoperatively, indoycine green fluorescent dye was injected into the anus to trace the No. 253 lymph nodes, and intraoperatively, arterial branching of the mesentery was performed by intravenous injection of fluorescent dye to preserve the left colic artery.
- interventionNames
- Device: Fluorescence laparoscopic system
- type
- ACTIVE_COMPARATOR
- label
- Performing laparoscopic No. 253 lymph node dissection and preserving the LCA.
- description
- Conventional laparoscopic approach for dissection of the No. 253 lymph nodes and preservation of the left colic artery.
- interventionNames
- Device: Fluorescence laparoscopic system
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Patients aged between 18 and 75 years * Colonoscopic biopsy confirmed colorectal adenocarcinoma * The tumor was located in the rectum or upper rectum, and the surgical method was Dxion * No local complications before operation (no obstruction, incomplete obstruction, no massive active bleeding, no perforation, abscess formation, no local invasion) * Preoperative imaging diagnosis was cT1-4aNxM0 * The hematopoietic functions of heart, lung, liver, kidney and bone marrow meet the requirements of surgery and anesthesia * Sign the informed consent form Exclusion Criteria: * Previous surgical history of malignant colorectal tumors * The surgical methods were combined abdominoperineal resection, Hartman operation and ISR operation * There are contraindication of laparoscopic surgery, such as severe cardiopulmonary insufficiency * Patients who have undergone multiple abdominal and pelvic surgeries or extensive abdominal adhesion * Patients with intestinal obstruction, intestinal perforation, intestinal bleeding and other emergency operations * ASA grade ≥IV and/or ECOG physical status score ≥2 points * Patients with severe liver and kidney function, cardiopulmonary function, coagulation dysfunction or combined with serious underlying diseases can not tolerate surgery * Have a history of serious mental illness * Patients with uncontrolled infection before operation
References
Publications (0)
Data not yet available
No reference posted for this study.