Clinical trial · Interventional
Enhancing Work Participation of Unemployed and Work-Disabled Cancer Survivors
Protocol of a Randomized Controlled Trial on the Effectiveness and Cost-effectiveness of a Supported Employment Intervention Aimed at Enhancing Work Participation of Unemployed or Work-disabled Cancer Survivors: the PLACES Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The primary objective of this study is to evaluate the effectiveness of the PLACES intervention on paid employment re-entry in unemployed and work-disabled cancer survivors, compared to CAU. Secondary Objectives are: * To evaluate the cost-effectiveness of the PLACES intervention aimed at unemployed or work-disabled cancer survivors. * To evaluate the effectiveness of the PLACES intervention on time until paid employment, type of employment, change in working hours, quality of life, quality of working life, work ability, and self-efficacy regarding RTW, in unemployed or work-disabled cancer survivors. * To evaluate the process of conducting the PLACES intervention in terms of recruitment, reach, dose delivered, dose received, fidelity and context. Participants in the intervention group will receive the PLACES intervention with a maximum duration of 1 year, and participants in the control group will receive CAU.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer Survivors | — | UNRESOLVED | — |
| Return to Work | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| PLACES | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- PLACES intervention
- description
- Participants in the intervention group will receive the PLACES intervention during 12-months after randomization.
- interventionNames
- Behavioral: PLACES
- type
- NO_INTERVENTION
- label
- Care as usual
- description
- Participants in the control group will receive usual care from the SSA.
Primary outcomes (1)
- measure
- Paid employment (yes/no)
- timeFrame
- 12 months
- description
- The primary outcome measure is paid employment (yes/no) at any point during the 1-year-follow-up. Being in paid employment is operationalised as working in a paid job for at least one hour per week as defined by the central statistics office.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
In order to be eligible for participation, participants must meet all of the following criteria: 1. Of working age (18-65 years); 2. Diagnosed with cancer between 6 months and 10 years ago; 3. Unemployed and either partially or fully work-disabled 4. They have completed their primary treatment (except long-term treatment such as hormone therapy); 5. An approved reintegration trajectory at the SSA; 6. Seeking paid employment and motivated to initiate work promptly. Cancer survivors who are unable to speak, read or understand the Dutch language and cancer survivors who got diagnosed with basal cell carcinoma will be excluded from participation.
References
Publications (1)
- DERIVEDvan Ommen F, Duijts SFA, Coenen P, Dalton SO, Kliffen A, van Hummel R, de Boer AGEM, Greidanus MA. Protocol of a randomized controlled trial on the effectiveness and cost-effectiveness of the PLACES intervention: a supported employment intervention aimed at enhancing work participation of unemployed and/or work-disabled cancer survivors. Trials. 2024 Sep 9;25(1):603. doi: 10.1186/s13063-024-08441-x. PMID 39252084