Clinical trial · Observational
A Clinical Prospective Study to Validate a Risk Scoring Model for the HMGC After Curative Surgery
A Clinical Prospective Study to Validate a Risk Scoring Model for the Hepatic Metastases From Gastric Cancer After Curative Surgery
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A previous study of investigators established a risk scoring model for occurrence of postoperative hepatic metastases in patients who underwent curative gastrectomy directly without neoadjuvant therapy. In order to further validate the clinical applicability of abovementioned model, investigators designed this prospective study, which also included patients who received neoadjuvant therapy before surgery, with the aim of exploring the applicability of the risk scoring model to this group of patients.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
| Hepatic Metastasis | — | UNRESOLVED | — |
| Predictive Cancer Model | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- with HMGC
- description
- patients with gastric cancer who developed hepatic metastasis after curative gastrectomy
- label
- without HMGC
- description
- patients with gastric cancer who did not developed hepatic metastasis after curative gastrectomy
Primary outcomes (1)
- measure
- hepatic metastasis
- timeFrame
- 2 years after curative surgery
- description
- Postoperative telephone follow-up was performed in patients with gastric cancer undergoing curative gastrectomy to determine the occurrence of hepatic metastasis.
Secondary outcomes (1)
- measure
- interval between the surgery and hepatic metastasis
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: 1. Received curative gastrectomy (D2 lymph node dissection); 2. Gastric cancer without distant organ metastasis, distant lymph node metastasis and peritoneal implantation (M0) confirmed by postoperative pathology; 3. No hepatic tumors and other occupying diseases, no chronic diseases such as cirrhosis and hepatitis, no hepatic schistosomiasis, no hepatic echinococcosis, no hepatic tuberculosis, and no severe fatty liver disease before the curative surgery; 4. No history of intraperitoneal chemotherapy; 5. No other serious concomitant diseases with satisfactory organ function; 6. No history of other malignant tumors; 7. Comply with the protocol during the whole study period; 8. Sign informed consent and permission of withdraw in the whole study period; 9. Estimation the overall survival after surgery no less than 12 months; 10. Consent to analysis of clinicopathological data and prognostic follow up; 11. Karnofsky Performance Scores (KPS) more than 60. Exclusion Criteria: 1. Special histological types of gastric cancer (neuroendocrine, squamous, squamous cell, hepatoid adenocarcinoma or others); 2. Gastro-esophageal junction cancer; 3. Severe congestive heart failure, frequent arrhythmia, or myocardial infarction within 12 months; 4. Immunosuppressive therapists for organ transplantation; 5. Seriously uncontrolled recurrent infection; 6. History of other malignancies; 7. No abilities of self-knowledge or mental disorders; 8. Combination of other serious diseases; 9. Concurrent participation in other clinical trials.
References
Publications (0)
Data not yet available