Clinical trial · Observational
Predictive Value of Epicardial Adipose Tissue for Pulmonary Embolism and Death in Patients With Lung Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): The number of patients is not sufficient to support the project.
Summary
Brief summary (as posted)
The occurrence and progression of lung cancer is related to visceral adipose tissue (VAT). Epicardial adipose tissue (EAT) is a kind of VAT, producing a variety of inflammatory cytokines and adipokines, participating in the formation of local inflammation, promoting the formation of pre-thrombotic state, and leading to the occurrence of thromboembolism. Patients with lung cancer have increased inflammatory response and are more prone to suffer thrombosis. However, in lung cancer patients, the clinical correlation between EAT and pulmonary embolism has not been reported. Objective: To analyze the risk factors of poor prognosis in lung cancer patients with PE, and to explore the predictive value of EAT in pulmonary embolism events and death in lung cancer patients. Methods: EAT volume and density, as well as anthropometric and blood biomarkers, were evaluated in a sample of lung cancer patients, half with pulmonary embolism and half without. The incidence of adverse prognosis and related factors were followed up by telephone.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Pulmonary Embolism | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| CTPA (computed tomography pulmonary angiography) | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- PE group
- description
- The CTPA diagnosis suggest pulmonary embolism
- interventionNames
- Diagnostic Test: CTPA (computed tomography pulmonary angiography)
- label
- control group
- description
- The CTPA diagnosis did not suggest pulmonary embolism
- interventionNames
- Diagnostic Test: CTPA (computed tomography pulmonary angiography)
Primary outcomes (2)
- measure
- EAT volume
- timeFrame
- May, 20, 2023
- description
- volume of epicardial adipose tissue (EAT), Cm3
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * The pathological diagnosis was lung cancer * Pulmonary artery was evaluated by CTA during hospitalization. Exclusion Criteria: * Patients with incomplete clinical data * Patients with no follow-up data * Patients with a history of PE before diagnosis of lung cancer
References
Publications (0)
Data not yet available