Clinical trial · Observational
Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics
Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics (PROSPECT): a National, Multicenter, Retrospective-prospective, Cohort Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The etiology and specific pathogenesis of many cardiovascular diseases such as coronary atherosclerosis, cardiomyopathy, atrial fibrillation, and stroke are still unclear. Improving diagnosis and treatment, clarifying the pathogenesis, and providing scientific basis for the prevention and treatment are hot research topics in the study of cardiovascular and cerebrovascular diseases. This study intends to collect clinical data and biological specimen data of patients with cardiovascular and cerebrovascular diseases who meet the inclusion and exclusion criteria, and use multi-omics technology to deeply understand the pathogenic mechanisms of cardiovascular and cerebrovascular diseases and provide new ideas for specific and individualized treatment of patients with cardiovascular and cerebrovascular diseases, to construct early predictive prognostic models and provide a basis for effective treatment of clinical practice in patients with cardiovascular and cerebrovascular diseases.
Conditions
Conditions (12)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Aortic Dissection | — | UNRESOLVED | — |
| Arrhythmias, Cardiac | — | UNRESOLVED | — |
| Brain Neoplasms | Brain Neoplasm | ONTOLOGY_EXACT | 0.90 |
| Cardiomyopathies | — | UNRESOLVED | — |
| Coronary Artery Disease | — | UNRESOLVED | — |
| Heart Neoplasms | Heart Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Heart Valve Diseases | — | UNRESOLVED | — |
| Hemorrhagic Cerebrovascular Disease | — | UNRESOLVED | — |
| Hypertension | — | UNRESOLVED |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Observational; No Interventions were given. | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (12)
- label
- Coronary artery disease group
- description
- Diagnosis of coronary artery disease by clinical guidelines.
- interventionNames
- Other: Observational; No Interventions were given.
- label
- Arrhythmia group
- description
- Diagnosis of arrhythmia by clinical guidelines. by clinical guidelines.
- interventionNames
- Other: Observational; No Interventions were given.
- label
- Heart valve disease group
- description
- Diagnosis of heart valve disease by clinical guidelines.
- interventionNames
- Other: Observational; No Interventions were given.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 3 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Patients who are regularly visited and followed up in the appropriate patient; department. * All patients met at least one of the following diagnostic criteria for cardiovascular and cerebrovascular diseases: * coronary artery disease group; * arrhythmia group; * heart valve disease group; * aortic dissection group; * cardiac masses group; * myocarditis group; * hypertension group; * cardiomyopathy group; * structural heart disease group; * ischemic cerebrovascular disease group; * hemorrhagic cerebrovascular disease group; * intracranial space occupying lesion group. Exclusion Criteria: * Age \<3 years or \>80 years old; * Pregnant and lactating women; * The patient declined to provide informed consent to participate in the study; * None of the above was met, but the patient was temporarily unable to sign the informed consent form due to coma and other reasons, and no legal representative signed it instead. Depending on the patient's condition, the patient may not be able to regain consciousness and sign the informed consent form.
References
Publications (0)
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