Empowering Patients' Lung Cancer Screening Uptake

Lung cancer is the leading cause of cancer related mortality. Lung cancer screening (LCS) with low dose computed tomography (LDCT) decreases mortality rate of lung cancer by 20%. Yet many patients who are eligible for lung cancer screening are still falling through the cracks which prevents patients the ability to detect lung cancer early. This study will test the effect of a a multi-level intervention on ordering LDCT within 6 months after patient enrollment. Our proposed intervention includes (1) Primary care provider notifications of patients' LCS eligibility; (2) patients' education ; (3) patients' referral to financial navigation resources; and (4) patients' reminder to discuss LCS during PCP visit.

Sex

All

Minimum age

50 Years

Maximum age

80 Years

Patients' Inclusion Criteria:

1. Aged 50- 80 years of age.
2. Be able to Speak English, Spanish, or Vietnamese
3. Must have a scheduled appointment with their Primary Care Providers within next one to three months.
4. The Scheduled PCP appointment is at any of the UCI Health primary care clinics in Orange County including two UCI federally qualified health centers
5. History of 20 pack year smoking history ( based on survey self report)
6. Current smoker or a former smoker who has quit smoking within the last 15 years (based on survey self report)

Patients' Exclusion Criteria:

1. Prior history of lung cancer
2. chest CT for any reason in the last 12 months based on self-report and UCI EMR
3. history of Alzheimer's disease or dementia

Providers' Inclusion Criteria:

1. Primary Care Providers whose patients were enrolled in the Empower LCS trial.
2. Received notifications about the eligibility of their patients for lung cancer screening.

• DERIVEDSharifian M, Hoyt MA, Madan A, Lee S, Nguyen TQ, Sadigh G. Patients' and Providers' Perspective of a Multi-level Approach to Improve Participation in Low-dose CT for Lung Cancer Screening (Empower LCS): A Mixed-Methods Analysis. Acad Radiol. 2026 Jun;33(6):2352-2360. doi: 10.1016/j.acra.2026.03.014. Epub 2026 Mar 28. PMID 41904093
• DERIVEDShojazadeh A, Kao R, Pham T, Madan A, Echeverria R, Chen WP, Nguyen V, Gutierrez O, Lee S, Hoyt MA, Ziogas A, Nguyen TQ, Keshava H, Sadigh G. A Multilevel Approach to Improve Participation in Low-Dose CT for Lung Cancer Screening (Empower LCS): A Single-Arm Pilot Feasibility Clinical Trial. J Am Coll Radiol. 2026 Apr;23(4):556-564. doi: 10.1016/j.jacr.2025.11.005. Epub 2025 Nov 13. PMID 41241060