Clinical trial · Interventional
Curcumin Gel On Radiation Induced Oral Mucositis
The Effect of Curcuma Long Oral Gel in Relation to Salivary Epidermal Growth Factor & Interleukin-8 on Radiation Induced Oral Mucositis in Iraqi Cancer Patients
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this clinical study is to investigate the effect of a curcuma longa oral gel (curenext) on reducing radiation-induced oral mucositis severity in cancer patients and provide a context for understanding if there is a relationship between the curcumin clinical effect and production of EGFs and IL8. Researchers will compare between curcumin group and standard treatment group.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
| Radiation-Induced Mucositis | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Curcumin Gel | Drug | — | UNRESOLVED |
| Standard Preparation | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Curcuma longa oral gel group
- interventionNames
- Drug: Curcumin Gel
- type
- ACTIVE_COMPARATOR
- label
- Standard treatment group
- interventionNames
- Drug: Standard Preparation
Primary outcomes (2)
- measure
- Onset of radiation induced mucositis
- timeFrame
- Assessment every week starting from first visit until the onset of mucositis (up to 2 months)
- description
- Onset (at which week) of radiation induced mucositis in relation to EGF and IL8
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 16 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Patients above 16 years having histopathologically confirmed cancer in head and neck region who planned to have radiation with head and neck mask. * Scheduled for 6-8 weeks of radiotherapy with 60-70Gy radiation (200cgy/fraction for 5 days/week). Exclusion Criteria: * patient with hodgkin lymphoma. * Any allergy to curcumin or other condiments.
References
Publications (0)
Data not yet available