Clinical trial · Interventional
The Development of a Metabolomic Test to Diagnose and Quantify Pancreatic Exocrine Insufficiency (The DETECTION Study)
NCT05980221CI-TRIAL-00068641DETECTIONunknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
DETECTION. The development of a metabolomic test to diagnose and quantify pancreatic exocrine insufficiency.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pancreatic Exocrine Insufficiency | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 13C MTGT | Diagnostic Test | — | UNRESOLVED |
| Metabolomics | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- OTHER
- label
- Pancreatic cancer (main cohort)
- description
- investigation of PEI and the metabolome of patients with pancreatic cancer in the fed and fasted state
- interventionNames
- Diagnostic Test: Metabolomics
- Diagnostic Test: 13C MTGT
- type
- OTHER
- label
- Sub-study cohorts: Chronic pancreatitis, cystic fibrosis, NET patients on SSAs
- description
- investigation of PEI and the metabolome of patients with other causes of PEI in the fed and fasted state
- interventionNames
- Diagnostic Test: Metabolomics
- Diagnostic Test: 13C MTGT
- type
- OTHER
- label
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 16 Years
Show eligibility criteria text
Inclusion Criteria: (for main pancreatic cancer cohort) * PDAC * PEI (as defined by breath test) * Tolerating oral diet Inclusion Criteria: (for CF cohort) * CF * PEI (as defined by breath test) * Tolerating oral diet Inclusion Criteria: (for CP cohort) * CP * PEI (as defined by breath test) * Tolerating oral diet Exclusion Criteria (all arms): * No other GI conditions * For each arm no evidence of the other arm conditions * For health controls, no history of CP, CF or pancreatic cancer * No GI surgery (except pancreatic resection in the pancreatic cancer cohort) * Unable to consent * Unable to travel to UHB for testing * Prognosis \< 2months * Performance status 2+
References
Publications (0)
Data not yet available
No reference posted for this study.