Clinical trial · Interventional
EXERT-BCN: an Exercise and Nutrition Regimen to Designed to Improve Body Composition After Treatment for Breast Cancer
An EXErcise Regimen Designed to Improve Body Composition, Functional Capacity, and Strength After Treatment for Breast Cancer with Nutrition Optimization
NCT05978960CI-TRIAL-00080966EXERT-BCNcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This protocol seeks to analyze patient outcomes of the standard of care, monitored group exercise regimen of high-load resistance training and functional exercises with compound movements in conjunction with a nutrition regimen focused on food quality under close supervision on women who have been treated for breast cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Nutrition and resistance training exercise intervention | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Resistance training with high quality low-carbohydrate nutrition regimen
- description
- The regimen will consist of an intense resistance training program with linear progression and the goal of increase strength, mobility, muscle mass, and functional capacity. The nutrition program will avoid calorie counting, and instead focus on quality, while maximizing protein and limiting carbohydrates.
- interventionNames
- Other: Nutrition and resistance training exercise intervention
Primary outcomes (2)
- measure
- Determine changes in fat mass in pounds from before to after the nutrition and exercise regimen via bioimpedance analysis
- timeFrame
- 3 months
- description
- Measurement on bioimpedance analysis machine (Inbody 970)
- measure
- Determine changes in fat mass in pounds from before to after the nutrition and exercise regimen via ultrasound
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 20 Years
- Maximum age
- 89 Years
Show eligibility criteria text
Inclusion Criteria: 1. Age 20-89 years 2. Women with a biopsy proven diagnosis of ductal carcinoma in situ or invasive carcinoma of the breast. 3. Women must have undergone treatment for breast cancer, including one or more of the following: surgery, radiation therapy, chemotherapy, immunotherapy, or hormonal therapy. Women undergoing active chemotherapy are not allowed on study. Treatment with targeted agents and immunotherapy is allowed. Exclusion Criteria: 1. Any current treatment with chemotherapy for breast cancer 2. Inability to get and down off the ground or squat body weight 3. Inability to safely engage in group sessions 4. Severe arthritic, joint, cardiovascular, or musculoskeletal condition deemed by PI to be unsafe to engage in resistance training
References
Publications (3)
- BACKGROUNDGardner CD, Trepanowski JF, Del Gobbo LC, Hauser ME, Rigdon J, Ioannidis JPA, Desai M, King AC. Effect of Low-Fat vs Low-Carbohydrate Diet on 12-Month Weight Loss in Overweight Adults and the Association With Genotype Pattern or Insulin Secretion: The DIETFITS Randomized Clinical Trial. JAMA. 2018 Feb 20;319(7):667-679. doi: 10.1001/jama.2018.0245. PMID 29466592
- BACKGROUNDChamp CE, Carpenter DJ, Diaz AK, Rosenberg J, Ackerson BG, Hyde PN. Resistance Training for Patients with Cancer: A Conceptual Framework for Maximizing Strength, Power, Functional Mobility, and Body Composition to Optimize Health and Outcomes. Sports Med. 2023 Jan;53(1):75-89. doi: 10.1007/s40279-022-01759-z. Epub 2022 Sep 29. PMID 36175646
- DERIVEDCarpenter DJ, Peluso C, Hilton C, Coopey SB, Gomez J, Rosenberg J, Beriwal S, Hyde PN, Champ CE. EXERT-BCN: An Exercise Regimen Designed to Improve Body Composition, Functional Capacity, and Strength After Treatment for Breast Cancer With Nutrition Optimization. JCO Oncol Pract. 2026 Feb;22(2):255-262. doi: 10.1200/OP-24-00954. Epub 2025 May 7. PMID 40334185